NCT07605169Active, not recruiting
Long-term Health and Economic Effects of an Individualized Lifestyle Intervention (LI-PAD-Extended)
Long-term Follow-up of Individualized Lifestyle Intervention Focused on Physical Activity and Diet: Effects on Weight Loss, Dietary Habits, Cardiovascular Health, Motivation, Health-related Quality of Life, and Health Economics (LI-PAD-Extended)
Source: ClinicalTrials.gov · Last updated 28 Aug 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if an individualized lifestyle intervention works to improve weight, diet, physical activity, cardiovascular health, health-related quality of life, and cost-effectiveness in overweight and obese adults aged 45-65 years. The main questions it aims to answer are: Does the intervention lead to sustained weight loss after 18 months? Does the intervention improve cardiovascular risk factors, metabolic markers, and health-related quality of life compared to general written advice? Is the intervention cost-effective? Researchers will compare the individualized lifestyle intervention to a control group that receives general written advice on physical activity and diet to see if the intervention provides greater long-term health and economic benefits. Participants will: Attend counseling sessions with a health promoter Take part in supervised aerobic and resistance training with a physiotherapist Use swimming facilities and participate in the Lifestyle School Access a digital health coach and the online Lifestyle Tool Complete measurements of body weight, diet, physical activity, and cardiovascular health markers (waist-to-hip ratio, blood pressure, blood lipids, fasting glucose, HbA1c, CRP, and liver enzymes) Complete assessments of resting energy expenditure, aerobic fitness, muscle strength, motivation, and health-related quality of life Provide blood samples at baseline, 6 months, and 18 months for dietary biomarker analysis Contribute data for health economic evaluation to assess cost-effectiveness
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 103 (estimated)
- First submitted
- 16 Feb 2026
- Start date
- 11 Aug 2025
- Primary completion date
- 25 May 2026
- Lead sponsor
- Vastra Gotaland Region
- Diseases
- Obesity
- NCT number
- NCT07605169
What you commit to
- Study type: Interventional
- Planned participants: 103
- From 11 Aug 2025 to the primary completion date, 25 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known coronary artery disease (clinical symptoms or earlier event)
- Severe illness or medical condition that, in the investigator's opinion, precludes participation in follow-up assessments
Other
- Inability to understand the language used in the study
- Inability to complete follow-up assessments at 18 months
Who the study is looking for
- Adults aged 45-65 years at baseline of the original LI-PAD study
- Body mass index (BMI) ≥28 and ≤34
- Completed the original LI-PAD study
- Able and willing to attend follow-up assessments and provide necessary data
- Able and willing to provide informed consent
Age in the registry: 45 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre for Lifestyle Intervention Coordinator of this site? Confirm its status | Gothenburg | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.