NCT07606677Not yet recruiting
Peripheral Blood CyTOF Immune Model for Cervical Lesion Detection in HPV16/18+ Women
Mass Cytometry-based Peripheral Blood Immune Model for Accurate Detection of Cervical Lesions in HPV16/18-positive Women: a Multicenter Study
Source: ClinicalTrials.gov · Last updated 26 May 2026
Brief summary (registry, in English)
This prospective, multicenter cohort study will recruit eligible HPV16/18-positive women from three tertiary hospitals in China. Peripheral blood samples and clinical data (cytology, HPV genotyping, colposcopy-directed biopsy) will be collected, followed by standardized mass cytometry (CyTOF) to develop and evaluate an immune model across cervical lesion grades.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 1465 (estimated)
- First submitted
- 6 May 2026
- Start date
- 15 May 2026
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- Women's Hospital School Of Medicine Zhejiang University
- Diseases
- Cervical cancer
- NCT number
- NCT07606677
What you commit to
- Study type: Observational
- Planned participants: 1465
- From 15 May 2026 to the primary completion date, 31 Mar 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior cervical ablation, cervical conization, chemoradiotherapy, or immunotherapy
Other illness
- Other malignancy within the past 2 years not in complete remission
- Presence of other systemic immune disease or active infection
Other
- Confirmed diagnosis of CIN2 or worse
- Pregnancy or lactation
- Inability to comply with follow-up and examinations
- Inability to comply with study procedures, restrictions, and requirements, as determined by the investigator
Who the study is looking for
- Availability of cervical cytology results
- Consent to colposcopy and cervical biopsy
- Signed informed consent
Age in the registry: 25 years to 65 years · Sex: Female · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.