NCT07607093Recruiting
Efficacy of Early Rhythm Control in AF With TR Patients
Source: ClinicalTrials.gov · Last updated 29 May 2026
Brief summary (registry, in English)
Atrial fibrillation is frequently accompanied by tricuspid regurgitation and may contribute to right atrial and tricuspid annular remodeling, leading to progression of tricuspid regurgitation and adverse clinical outcomes. However, whether early rhythm control improves prognosis in patients with atrial fibrillation and tricuspid regurgitation remains unclear. This study will compare early rhythm control with usual care in these patients, using a composite outcome of cardiac death, heart failure admission, stroke, and tricuspid valve surgery.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 5800 (estimated)
- First submitted
- 19 May 2026
- Start date
- 18 Feb 2026
- Primary completion date
- 28 Feb 2027
- Lead sponsor
- Samsung Medical Center
- Diseases
- Atrial fibrillation
- NCT number
- NCT07607093
What you commit to
- Study type: Observational
- Planned participants: 5800
- From 18 Feb 2026 to the primary completion date, 28 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with CIED implantation prior to the diagnosis of tricuspid regurgitation
- Patients diagnosed with TR only after the initiation of rhythm control therapy for AF
Other illness
- Patients with a history of valvular surgery
- Patients with congenital heart disease
- Patients with primary pulmonary hypertension
Who the study is looking for
- Patients with concomitant atrial fibrillation and tricuspid regurgitation.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Samsung Medical Center Coordinator of this site? Confirm its status | Seoul | South Korea | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.