NCT07608003Recruiting
Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis:
Application of MRI-Based Artificial Intelligence Models for Preoperative Molecular Subtyping and Prognostic Assessment of Midline Gliomas: A Multicenter Prospective Clinical Study
Source: ClinicalTrials.gov · Last updated 27 May 2026
Brief summary (registry, in English)
A vision-language model using preoperative MRI and clinical variables has been developed to simultaneously predict three key molecular markers in midline gliomas: H3K27M, IDH, and 1p/19q. This prospective multicenter study will validate the model's accuracy in preoperative molecular subtyping and its value in prognostic assessment and clinical decision-making across multiple neurosurgical centers.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 7 May 2026
- Start date
- 10 May 2026
- Primary completion date
- 31 Dec 2030
- Lead sponsor
- Xiangya Hospital of Central South University
- Diseases
- Glioblastoma, Childhood cancers
- NCT number
- NCT07608003
What you commit to
- Study type: Observational
- Planned participants: 500
- From 10 May 2026 to the primary completion date, 31 Dec 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- The tumor is not located in the intracranial midline.
- Cases in which MRI were incomplete or with significant noise and artifacts.
Who the study is looking for
- Patients with diffuse gliomas were pathologically and molecularly diagnosed.
- The clinical case data of all patients were complete.
- Patients underwent preoperative MRI examination.
Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Xiangya Hospital of Central South University Coordinator of this site? Confirm its status | Changsha | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.