NCT07608601Completed
Latent Tuberculosis Infection Screening Using QuantiFERON at Pre-Employment Assessment in Hospital Workers CHu Nice
Relevance of Systematic Latent Tuberculosis Infection Screening Using QuantiFERON at Pre-Employment Assessment in Hospital Workers: A Retrospective Study at the University Hospital of Nice
Source: ClinicalTrials.gov · Last updated 2 Sept 2026
Brief summary (registry, in English)
This retrospective observational single-center study aims to evaluate the medical and occupational relevance of systematic screening for latent tuberculosis infection using QuantiFERON-TB Gold Plus during pre-employment occupational health assessment among hospital workers at the University Hospital of Nice. Data will be collected retrospectively from occupational health medical records, immunology laboratory results and, when necessary, data from specialized follow-up by the tuberculosis control center. The primary objective is to determine the proportion of positive QuantiFERON-TB Gold Plus tests at pre-employment screening. Secondary objectives are to identify factors associated with a positive test, to describe the practical consequences of screening, including chest X-ray, diagnosis of latent tuberculosis infection and initiation of preventive treatment, and to estimate the cost of systematic screening.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1185 (actual)
- First submitted
- 20 May 2026
- Start date
- 1 Apr 2024
- Primary completion date
- 30 Apr 2026
- Lead sponsor
- Centre Hospitalier Universitaire de Nice
- Diseases
- Tuberculosis
- NCT number
- NCT07608601
What you commit to
- Study type: Observational
- Participants enrolled: 1185
- From 1 Apr 2024 to the primary completion date, 30 Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Incomplete or unusable occupational health records.
- Indeterminate QuantiFERON-TB Gold Plus results will be included in the descriptive analysis but excluded from comparative analyses of test positivity.
Who the study is looking for
- Newly recruited hospital workers at the University Hospital of Nice.
- Workers who underwent pre-employment occupational health assessment during the study period.
- Workers who had a QuantiFERON-TB Gold Plus test performed as part of pre-employment screening.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Nice Coordinator of this site? Confirm its status | Nice | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.