NCT07611019Enrolling by invitationPhase 2/3
Colchicine for the Prevention of Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Single-Center, Strategy-Stratified, Randomized, Double-Blind, Placebo-Controlled Trial
Randomized, Double-Blind, Placebo-Controlled Trial of Colchicine to Prevent Post-Operative Atrial Fibrillation After CABG With Strategy-Stratified Randomization
Source: ClinicalTrials.gov · Last updated 10 Jul 2026
Brief summary (registry, in English)
Post-operative atrial fibrillation after coronary artery bypass grafting (CABG)
- Status (registry)
- Enrolling by invitation
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 400 (estimated)
- First submitted
- 24 Feb 2026
- Start date
- 6 Jul 2026
- Primary completion date
- Jul 2028
- Lead sponsor
- National Taiwan University Hospital
- Diseases
- Atrial fibrillation
- NCT number
- NCT07611019
What you commit to
- Study type: Interventional · Phase 2/3
- Planned participants: 400
- From 6 Jul 2026 to the primary completion date, Jul 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Known hypersensitivity or previous severe adverse reaction to colchicine.
- Current use of strong CYP3A4 or P-glycoprotein inhibitors that cannot be safely discontinued or substituted.
Other illness
- History of atrial fibrillation or atrial flutter before surgery.
- Severe renal impairment (estimated glomerular filtration rate \<30 mL/min/1.73 m²) or chronic dialysis.
- Any condition judged by the investigators to interfere with study participation or safety assessment.
Other
- Severe hepatic dysfunction.
- Pregnancy or breastfeeding.
Who the study is looking for
- Adults aged 20 years or older scheduled to undergo elective coronary artery bypass grafting (CABG), including either off-pump CABG or on-pump CABG.
- Ability to receive oral study medication before and after surgery.
- Provision of written informed consent before randomization.
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Taiwan University Hospital Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.