NCT07612748Recruiting
Two Different Endoscopic Treatments for Rectal Neuroendocrine Neoplasms
Retrospective Comparative Study of Two Different Endoscopic Treatments for Rectal Neuroendocrine Neoplasms
Source: ClinicalTrials.gov · Last updated 3 Jun 2026
Brief summary (registry, in English)
The aim is to compare the safety and efficacy of endoscopic submucosal dissection (ESD) versus endoscopic partial muscle resection（ EPMR） for the treatment of rectal neuroendocrine neoplasms (R-NENs), thereby providing guidance for optimizing therapeutic strategies. The investigators retrospectively analyzed consecutive patients with R-NENs who underwent endoscopic resection at our center between January 2020 and February 2026. Patients were assigned to either the ESD group or the EPMR group. Baseline characteristics and perioperative outcomes were compared, including the number of lesions, maximum lesion diameter, single-lesion procedure time, postoperative complications, positive margin rate, pathological staging, lymphovascular invasion, and the need for additional therapies.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 483 (estimated)
- First submitted
- 21 May 2026
- Start date
- 1 Jun 2026
- Primary completion date
- 1 Nov 2026
- Lead sponsor
- Jilin University
- Diseases
- Neuroendocrine tumours
- NCT number
- NCT07612748
What you commit to
- Study type: Interventional
- Planned participants: 483
- From 1 Jun 2026 to the primary completion date, 1 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of non-ESD or non-EPMR endoscopic techniques, such as ligation-assisted resection or Endoscopic Mucosal Resection (EMR).
Other illness
- Presence of other conditions deemed by the investigator to be unsuitable for participation in this study.
Other
- Patient or family refusal to participate.
Who the study is looking for
- Patients undergoing endoscopic treatment for rectal neuroendocrine neoplasms.
- Lesion diameter less than 2 cm.
- Preoperative auxiliary examinations indicating no peripheral lymph node or distant metastasis.
- Endoscopic surgical approach limited to ESD or EPMR.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Hospital of Jilin University Coordinator of this site? Confirm its status | Changchun | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.