NCT07613632Recruiting
Changes in Regional Ventilation-Perfusion Match Following Percutaneous Transluminal Angioplasty for Arteriovenous Graft Thrombosis
Changes in Regional Ventilation-Perfusion Match Following Percutaneous Transluminal Angioplasty for Arteriovenous Graft Thrombosis: A Prospective Observation Pilot Study
Source: ClinicalTrials.gov · Last updated 29 May 2026
Brief summary (registry, in English)
Patients with end-stage renal disease (ESRD) often require arteriovenous grafts (AVG) for hemodialysis. AVG thrombosis is a common complication, usually managed by percutaneous transluminal angioplasty (PTA) to restore blood flow. PTA achieves patency by balloon-mediated compression and fragmentation of thrombus. Small thrombus fragments may enter the venous circulation and cause transient pulmonary microembolism, leading to ventilation-perfusion (V/Q) mismatch. This study uses electrical impedance tomography (EIT) to noninvasively monitor short-term changes in regional ventilation and perfusion during and after PTA, exploring the immediate pulmonary physiological consequences of thrombus fragmentation and revascularization in dialysis patients.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 20 (estimated)
- First submitted
- 23 May 2026
- Start date
- Oct 2024
- Primary completion date
- Sept 2027
- Lead sponsor
- First Affiliated Hospital of Wannan Medical College
- Diseases
- Chronic kidney disease
- NCT number
- NCT07613632
What you commit to
- Study type: Observational
- Planned participants: 20
- From Oct 2024 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe respiratory failure incompatible with supine position.
- Thoracic skin condition or deformity preventing EIT electrode placement.
- NYHA Class IV heart failure or hemodynamic instability.
Other
- Acute pulmonary embolism or acute pulmonary edema before procedure.
- Pregnancy or breastfeeding.
- Any other circumstance judged unsuitable by investigator.
Who the study is looking for
- Age ≥ 18 years.
- Diagnosis of end-stage renal disease receiving maintenance hemodialysis.
- Documented AVG thrombosis requiring PTA.
- Able to cooperate and tolerate EIT monitoring.
- Provided written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College) Coordinator of this site? Confirm its status | Wuhu | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.