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NCT07615569Completed

Robot-assisted Versus Conventional Physical Therapy for Hand in Sub-acute Stroke

Source: ClinicalTrials.gov · Last updated 7 Jul 2026

Brief summary (registry, in English)

This randomized controlled trial aims to compare the effectiveness of robotic-assisted physiotherapy and conventional physiotherapy in improving hand function among patients with sub-acute stroke. Stroke often results in weakness, reduced hand strength, impaired dexterity, and difficulty performing daily activities due to upper-limb motor dysfunction. Early rehabilitation targeting hand recovery is essential to improve independence and quality of life. A total of 30 participants with sub-acute post-stroke spastic hemiplegia will be recruited from the University of Lahore Hospital and randomly assigned into two groups. The intervention group will receive robotic-assisted physiotherapy focused on repetitive, task-specific wrist and finger extension training using a robotic hand/wrist device, while the control group will receive conventional therapist-led upper-limb rehabilitation exercises. Both groups will undergo treatment sessions lasting 30-45 minutes, five days per week for four weeks. Outcome measures will include hand muscle strength assessed using a hand-held dynamometer, hand dexterity evaluated through the Action Research Arm Test (ARAT), and functional improvement measured using the Fugl-Meyer Assessment for Upper Extremity (FMA-UE). Additional measures such as spasticity, activities of daily living, and quality of life will also be recorded. Assessments will be conducted at baseline, during treatment, and after completion of the intervention period by a blinded assessor. The study is expected to determine whether robotic-assisted physiotherapy provides greater improvements in hand strength, dexterity, and upper-limb functional recovery compared to conventional physiotherapy in individuals recovering from stroke. Findings from this research may contribute to evidence-based rehabilitation strategies for improving upper-limb outcomes after stroke.

Status (registry)
Completed
Study type
Interventional
Enrollment
30 (actual)
First submitted
22 May 2026
Start date
22 May 2026
Primary completion date
22 Jun 2026
Lead sponsor
Montiha Azeem
Diseases
Stroke
NCT number
NCT07615569

What you commit to

  • Study type: Interventional
  • Participants enrolled: 30
  • From 22 May 2026 to the primary completion date, 22 Jun 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Participation in any intensive upper-limb rehabilitation program (CIMT, bimanual training, task-specific training, robotic therapy, FES therapy) within the past 6 months.

Other illness

  • No history of upper-limb orthopedic surgery or botulinum toxin injections in the last 6 months.
  • History of recurrent or uncontrolled seizure disorders, progressive neurological diseases, or unstable cardiovascular conditions.
  • Comorbid conditions affecting upper-limb function (fractures, severe arthritis, peripheral nerve injuries).

Who the study is looking for

  • Both male and female adults aged 30-50 years diagnosed with post-stroke spastic hemiplegia confirmed by a neurologist.
  • Stroke duration 2 weeks to 6 months (sub acute stage) with medically stable condition.
  • Presence of mild to moderate upper-limb spasticity using screening test(Modified Ashworth Scale score 1-3).
  • Ability to comprehend and follow simple verbal instructions using screening test (MMSE ≥ 24).

Age in the registry: 30 years to 50 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Lahore Teaching Hospital, Lahore
Coordinator of this site? Confirm its status
LahorePakistanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.