NCT07616024Not yet recruiting
Intravascular Ultrasound guidaNce versuS angIoGrapHy Guidance in Patients With ST-segment Elevation Myocardial Infarction
Intravascular Ultrasound guidaNce versuS angIoGrapHy Guidance in Primary percuTaneous Coronary Intervention for Patients With ST-segment Elevation Myocardial Infarction
Source: ClinicalTrials.gov · Last updated 18 Jun 2026
Brief summary (registry, in English)
STEMI represents the subtype of ACS with the worst prognosis, associated with high mortality and an elevated risk of complications. The use of IVI guidance holds the potential to reduce the incidence of MACE. In previous studies, there has been limited research on intravascular imaging in the context of primary revascularization procedures for STEMI, and no large-scale cohort study has compared the differences in clinical outcomes between IVI-guided and angiography-guided primary revascularization. Therefore, we conducted this large-scale randomized controlled trial to compare IVI-guided primary PCI versus coronary angiography-guided primary PCI in patients with STEMI.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 2488 (estimated)
- First submitted
- 18 May 2026
- Start date
- 1 Jun 2026
- Primary completion date
- 31 Dec 2032
- Lead sponsor
- Shanghai Zhongshan Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT07616024
What you commit to
- Study type: Interventional
- Planned participants: 2488
- From 1 Jun 2026 to the primary completion date, 31 Dec 2032
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who have previously undergone coronary artery bypass grafting (CABG);
- Patients who are expected to be intolerant to long-term antiplatelet therapy;
- Currently participating in another drug/device clinical trial and not having reached the primary endpoint;
Other illness
- Patients with cardiogenic shock or severe heart failure (Killip class IV);
Other
- Patients with coma or disturbance of consciousness;
- Pregnant women;
- Life expectancy \< 1 year;
- Poor compliance, expected to be unable to complete follow-up.
Who the study is looking for
- Patients diagnosed with acute ST-segment elevation myocardial infarction (STEMI) who have an indication for emergency interventional therapy;
- Subjects who are eligible to undergo primary percutaneous coronary intervention (PCI);
- Subjects or their authorized family members voluntarily agree to participate in the clinical trial and sign the written informed consent form;
- The IVUS catheter is expected to pass through the target lesion to complete the examination.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Zhongshan Hospital Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.