NCT07616050Not yet recruiting
Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients
Evaluation of the Impact of a Rehabilitation Intervention Based on Cycling With Virtual Park on Training Motivation in Adult Patients
Source: ClinicalTrials.gov · Last updated 29 May 2026
Brief summary (registry, in English)
The purpose of this clinical study is to evaluate the feasibility, usability, and motivational impact of VirtualPark, a virtual reality-based dual-task rehabilitation system, in adults with neurological and age-related conditions. VirtualPark is a virtual reality application designed to deliver cognitive exercises during cycling training using a commercially available ergometer (THERA-Trainer Tigo). The system integrates physical and cognitive tasks in simulated real-life environments. The intervention integrates motor and cognitive training tasks targeting domains such as attention, inhibition, working memory, and navigation. This is a prospective, multicenter, randomized, cross-over pilot study. It will compare cycling training performed with and without virtual reality. Participants will complete both intervention conditions over a 4-week period separated by a wash-out phase with standard rehabilitation activities. The order of conditions will be randomized. The study will assess motivation during rehabilitation training, usability and user experience of the system, as well as exploratory effects on cognitive and motor performance, functional abilities, perceived exertion, and safety. The study will enroll adult participants (≥18 years) with conditions such as stroke, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, mild cognitive impairment, spinal cord injury, and frail older adults.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 15 May 2026
- Start date
- Jun 2026
- Primary completion date
- Dec 2026
- Lead sponsor
- Marta Mondellini
- NCT number
- NCT07616050
What you commit to
- Study type: Interventional
- Planned participants: 70
- From Jun 2026 to the primary completion date, Dec 2026
- 7 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Other concomitant neurological pathologies in addition to the one under study
Other
- presence of visual disturbances that do not allow access to the experimental virtual reality protocol
- presence of impaired cardiorespiratory function or other organic instabilities that contraindicate ergometer training
- severe osteoporosis
Who the study is looking for
- Informed consent to the study
- subjects \> 18 years and \<85 years
- diagnosis of MCI according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders VTh Edition (DSM V TR American Psychological Association 2013)
- detection of ischemic stroke within 6 months preceding the study, frail elderly subjects (Gobbens RJ et al. 2010)
- subjects affected by idiopathic Parkinson's disease according to the MDS-PD criteria (Postuma et al., 2015)
- subjects affected by possible, probable and definite ALS according to the revised El Escorial criteria (Brooks Br, et al. 2000)
- subjects affected by MS according to the McDonald criteria (2017) with disability measured with the EDSS (Expanded Disability Status Scale) \<= 8
- patients with spinal cord injury of different etiology with incomplete spinal cord injury, AIS (ASIA impairment scale) grade C and D, MMSE \>18
- subjects naïve to the use of the RV
- no therapeutic changes or rehabilitation interventions in the month prior to inclusion in the study
- no ongoing behavioral disorders.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Istituti a Carattere Scientifico Maugeri Bari Coordinator of this site? Confirm its status | Bari | Italy | Unknown status |
| Centro di Riabilitazione Villa Beretta Coordinator of this site? Confirm its status | Costa Masnaga | Italy | Unknown status |
| Istituti a Carattere Scientifico Maugeri Milano Camaldoli Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| Istituti a Carattere Scientifico Maugeri Montescano Coordinator of this site? Confirm its status | Montescano | Italy | Unknown status |
| Istituti a Carattere Scientifico Maugeri Pavia Coordinator of this site? Confirm its status | Pavia | Italy | Unknown status |
| Università di Pisa Coordinator of this site? Confirm its status | Pisa | Italy | Unknown status |
| Istituti a Carattere Scientifico Maugeri Telese Coordinator of this site? Confirm its status | Telese Terme | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.