NCT07617974Recruiting
Natural History of Atrial Fibrillation-Induced Tricuspid Valve Remodeling in the Absence of Significant Tricuspid Regurgitation: A Three-Dimensional Echocardiographic Study
Natural History of Atrial Fibrillation-Induced Tricuspid Valve Remodeling in the Absence of Significant Tricuspid Regurgitation: A Three-Dimensional Echocardiographic Study (TRICUSPID-AF)
Source: ClinicalTrials.gov · Last updated 1 Jun 2026
Brief summary (registry, in English)
This is a prospective, observational, multicenter study aimed at characterizing tricuspid valve remodeling in patients with atrial fibrillation (AF) without significant tricuspid regurgitation (TR), in relation to AF burden progression.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 66 (estimated)
- First submitted
- 8 May 2026
- Start date
- 4 May 2026
- Primary completion date
- 31 May 2027
- Lead sponsor
- Centro Cardiologico Monzino
- Diseases
- Atrial fibrillation
- NCT number
- NCT07617974
What you commit to
- Study type: Observational
- Planned participants: 66
- From 4 May 2026 to the primary completion date, 31 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior AF ablations;
Other illness
- Arrhythmias other than AF;
Other
- Moderate or greater TR assessed using a multiparametric approach;
- Rapid ventricular response (average HR \>110 bpm) during baseline TTE;
- Inadequate image quality
Who the study is looking for
- Consecutive patients with atrial fibrillation (paroxysmal or persistent) undergoing transthoracic echocardiography (TTE) prior to AF ablation with acquisition of a 3D TV dataset.
- Eligible for enrollment in the control group will be:
- all consecutive patients with structurally normal hearts and no history of AF or;
- moderate atrial functional tricuspid regurgitation and AF, in the absence of significant left-sided valvular disease or prior valvular surgery.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centro Cardiologico Monzino IRCCS Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.