NCT07622914Recruiting
The Role of Dietary Fiber in Mitigating Sarcopenia Risk in Head and Neck Cancer
A Preliminary Elucidation of the Role of Dietary Fiber in Mitigating Sarcopenia Risk in Head and Neck Cancer
Source: ClinicalTrials.gov · Last updated 3 Jun 2026
Brief summary (registry, in English)
Emerging data suggest consumption of dietary fiber before and during cancer treatment may improve prognosis for patients with head and neck cancer, in part via increased production of short chain fatty acids, systemic anti-inflammatory effects, and decreased risk of sarcopenia. Foods rich in dietary fiber are often low in calories and protein, thus are not typically targeted in current treatment paradigms that focus on countering the catabolic state associated with sarcopenia. This project entails an observational, mixed methods study to: observe dietary fiber intake in patients with head and neck cancer from time of diagnosis for six months; elucidate the relationship between dietary fiber intake, short chain fatty acids, inflammatory markers, and sarcopenia; and explore the feasibility of and patient perceptions regarding promoting dietary fiber as part of their treatment approaches.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 59 (estimated)
- First submitted
- 18 Jul 2025
- Start date
- 31 Oct 2025
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- University of Oklahoma
- Diseases
- Head and neck cancer
- NCT number
- NCT07622914
What you commit to
- Study type: Observational
- Planned participants: 59
- From 31 Oct 2025 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previously diagnosed or positive screen for a GI-related condition or eating disorder
Other
- Able to complete bioelectrical impedance (stand unsupported, no pacemaker or limb amputation) and Timed Chair Stands
- Currently pregnant, planning to become pregnant, or breastfeeding
- Current or past 3-month antibiotic use
Who the study is looking for
- ≥18 years of age
- Newly diagnosed with squamous cell carcinoma of the: paranasal sinuses, nasal cavity, oral cavity, tongue, larynx, pharynx \[i.e., nasopharynx, oropharynx, hypopharynx\]
- Meeting at least 60% of baseline energy needs
- Willingness to provide data prior to treatment
- Access to the internet
- Access to a home freezer
- Ability to do remote interview
- Access to a phone
- Willingness to avoid pre-, pro-, or synbiotics
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Stephenson Cancer Center Coordinator of this site? Confirm its status | Oklahoma City | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.