NCT07623668RecruitingPhase 3
Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research
A Randomized, Double-masked, Placebo-controlled Study Assessing the Efficacy and Safety of Privosegtor (OCS-05) in Patients With Optic Neuritis (ON)
Source: ClinicalTrials.gov · Last updated 14 Aug 2026
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate the safety and efficacy of privosegtor, a neuroprotective candidate, in patients diagnosed with optic neuritis (ON). Researchers will compare privosegtor and the standard of care (methylprednisolone) to a placebo and standard of care (methylprednisolone).
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 210 (estimated)
- First submitted
- 28 May 2026
- Start date
- 28 May 2026
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Oculis
- Diseases
- Multiple sclerosis
- NCT number
- NCT07623668
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 210
- From 28 May 2026 to the primary completion date, 31 Dec 2027
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- \- Have a history or presence of any disorder or condition that may, in the opinion of the Investigator, likely interfere with the interpretation of the study results or participant safety
Who the study is looking for
- Adult men and women (aged 18 to 50 years) with the first episode of ON in the study eye, associated with unilateral visual loss.
- Onset of visual loss symptoms in the previous 12 days before first administration of study treatment.
Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of South Carolina, Storm Eye Institute Coordinator of this site? Confirm its status | Charleston | United States | Recruiting |
| UT Southwestern Medical Center (Ophthalmology CRU) Coordinator of this site? Confirm its status | Dallas | United States | Recruiting |
| Neuro-Eye Clinical Trials Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
| Kahana Oculoplastic and Orbital Surgery Coordinator of this site? Confirm its status | Livonia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.