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NCT07624630Recruiting

Walking and Thinking - Brain Activity During Complex Walking in Stroke

Source: ClinicalTrials.gov · Last updated 3 Jun 2026

Brief summary (registry, in English)

Everyday life requires individuals to function in complex environments and perform tasks that involve the integration of motor and cognitive abilities. However, stroke often leads to impairments in motor-cognitive interaction, which can negatively affect mobility, balance, attention, and the ability to live independently. Although motor-cognitive performance has been identified as an important rehabilitation target after stroke, limited knowledge exists regarding the underlying brain function associated with these difficulties and how rehabilitation and exercise interventions can best address them. Improving treatment for motor-cognitive difficulties after stroke, such as dual-task walking and navigation, remains a major challenge. An important step is developing assessment methods that accurately capture these impairments in ecologically valid settings that reflect real-world mobility demands. The investigators therefore aim to explore brain function during complex walking after stroke by investigating motor-cognitive performance and its neural correlates during three walking conditions: dual-task walking, navigation, and a combination of both. Non-invasive measures of brain activity using functional near-infrared spectroscopy (fNIRS) together with advanced real-time gait analysis will be used to better understand how stroke affects motor-cognitive functioning during complex walking tasks.

Status (registry)
Recruiting
Study type
Observational
Enrollment
50 (estimated)
First submitted
13 May 2026
Start date
1 Aug 2026
Primary completion date
1 Jul 2027
Lead sponsor
Karolinska Institutet
Diseases
Stroke
NCT number
NCT07624630

What you commit to

  • Study type: Observational
  • Planned participants: 50
  • From 1 Aug 2026 to the primary completion date, 1 Jul 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Individuals post stroke with cognitive impairment

Other

  • severe neglect
  • global aphasia affecting the ability to provide written informed consent
  • severe perceptual problems or severe freezing of gait

Who the study is looking for

  • 18 years or older
  • with a stroke ≥6 months confirmed by a clinical diagnosis
  • with the ability to walk with or without a walking aid for ≥ 5 min

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
uMOVE core facility, Karolinska Institutet and Karolinska University hospital
Coordinator of this site? Confirm its status
SolnaSwedenRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.