NCT07624630Recruiting
Walking and Thinking - Brain Activity During Complex Walking in Stroke
Source: ClinicalTrials.gov · Last updated 3 Jun 2026
Brief summary (registry, in English)
Everyday life requires individuals to function in complex environments and perform tasks that involve the integration of motor and cognitive abilities. However, stroke often leads to impairments in motor-cognitive interaction, which can negatively affect mobility, balance, attention, and the ability to live independently. Although motor-cognitive performance has been identified as an important rehabilitation target after stroke, limited knowledge exists regarding the underlying brain function associated with these difficulties and how rehabilitation and exercise interventions can best address them. Improving treatment for motor-cognitive difficulties after stroke, such as dual-task walking and navigation, remains a major challenge. An important step is developing assessment methods that accurately capture these impairments in ecologically valid settings that reflect real-world mobility demands. The investigators therefore aim to explore brain function during complex walking after stroke by investigating motor-cognitive performance and its neural correlates during three walking conditions: dual-task walking, navigation, and a combination of both. Non-invasive measures of brain activity using functional near-infrared spectroscopy (fNIRS) together with advanced real-time gait analysis will be used to better understand how stroke affects motor-cognitive functioning during complex walking tasks.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 13 May 2026
- Start date
- 1 Aug 2026
- Primary completion date
- 1 Jul 2027
- Lead sponsor
- Karolinska Institutet
- Diseases
- Stroke
- NCT number
- NCT07624630
What you commit to
- Study type: Observational
- Planned participants: 50
- From 1 Aug 2026 to the primary completion date, 1 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Individuals post stroke with cognitive impairment
Other
- severe neglect
- global aphasia affecting the ability to provide written informed consent
- severe perceptual problems or severe freezing of gait
Who the study is looking for
- 18 years or older
- with a stroke ≥6 months confirmed by a clinical diagnosis
- with the ability to walk with or without a walking aid for ≥ 5 min
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| uMOVE core facility, Karolinska Institutet and Karolinska University hospital Coordinator of this site? Confirm its status | Solna | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.