NCT07628257Not yet recruiting
Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of DTI and Rs-fMRI to a Preoperative FDG PET Strategy, With Neuropsychological Correlates and Post-treatment Follow-up
Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of Diffusion Tensor Imaging (DTI) and Resting State Functional MRI (Rs-fMRI) to a Preoperative FDG PET Strategy, With Neuropsychological Correlates and Post-treatment Follow-up
Source: ClinicalTrials.gov · Last updated 4 Jun 2026
Brief summary (registry, in English)
The aim of this study is to determine whether the diffuse cerebral metabolic disturbances observed in glioblastoma are exclusively linked to the direct and indirect effects of tumor infiltration (particularly structural disconnection), or whether they also reflect a more global alteration of neurometabolic and neurovascular coupling mechanisms. This approach thus aims to better understand the pathophysiological basis of cognitive impairment in glioblastoma and to characterize the impact of the disease at the level of brain networks.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 28 May 2026
- Start date
- 15 Sept 2026
- Primary completion date
- 15 Sept 2030
- Lead sponsor
- Centre Paul Strauss
- Diseases
- Glioblastoma
- NCT number
- NCT07628257
What you commit to
- Study type: Interventional
- Planned participants: 80
- From 15 Sept 2026 to the primary completion date, 15 Sept 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Contraindications to MRI
- Minor or incapacitated adult
- Patient deprived of liberty
- Patient under legal guardianship
- Patient unable to consent
- Pregnant or breastfeeding woman
Who the study is looking for
- Adult patients
- Patients with glioblastoma
- Patients treated in the Nuclear Medicine \& Molecular Imaging Department of the Strauss Institute for PET/MRI scans for:
- Preoperative metabolic evaluation of a brain-expanding lesion
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institut public de cancérologie Strauss Europe Coordinator of this site? Confirm its status | Strasbourg | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.