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NCT07629102Completed

Perioperative Respiratory Function in Sleeve Gastrectomy

Perioperative Oxygenation and Respiratory Function in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy: A Retrospective Cohort Study

Source: ClinicalTrials.gov · Last updated 5 Jun 2026

Brief summary (registry, in English)

This retrospective single-center cohort study aims to evaluate the effects of two intraoperative ventilation strategies on perioperative oxygenation and respiratory outcomes in obese patients undergoing laparoscopic sleeve gastrectomy. Patients were managed using standardized anesthetic and ventilatory protocols with volume-controlled ventilation and fixed inspired oxygen fraction (FiO₂ 45%). The study compares conventional ventilation with PEEP 5 cmH₂O versus a protective ventilation strategy consisting of PEEP 8 cmH₂O combined with repeated recruitment maneuvers performed after pneumoperitoneum establishment and before extubation. Perioperative oxygenation is assessed using serial PaO₂/FiO₂ measurements obtained immediately after intubation, after pneumoperitoneum establishment, and after extubation. Secondary outcomes include perioperative arterial blood gas variables, postoperative spirometric parameters, lactate levels, ICU admission, and hospital length of stay. The study aims to determine whether escalation of intraoperative ventilatory support provides incremental respiratory benefit in contemporary bariatric anesthesia practice.

Status (registry)
Completed
Study type
Interventional
Enrollment
53 (actual)
First submitted
22 May 2026
Start date
Apr 2026
Primary completion date
Apr 2026
Lead sponsor
Istanbul Saglik Bilimleri University
Diseases
Obesity
NCT number
NCT07629102

What you commit to

  • Study type: Interventional
  • Participants enrolled: 53
  • From Apr 2026 to the primary completion date, Apr 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • revision bariatric surgery
  • gastric bypass surgery
  • conversion to open surgery

Other

  • incomplete perioperative records
  • missing arterial blood gas measurements
  • unavailable postoperative pulmonary function tests

Who the study is looking for

  • \- American Society of Anesthesiologists (ASA) physical status I-III who underwent elective laparoscopic sleeve gastrectomy

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Başakşehir Çam and Sakura City Hospital
Coordinator of this site? Confirm its status
IstanbulTurkey (Türkiye)Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.