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NCT07629375Recruiting

Standardization of a Platform of Preclinical Models Derived From NSCLC Patients

Standardization of a Platform of Preclinical Models Derived From NSCLC Patients to Investigate the Efficacy of New Nutraceutical Compounds Used as Monotherapy or in Combination With Immunotherapeutics or Chemo-immunotherapy

Source: ClinicalTrials.gov · Last updated 5 Jun 2026

Brief summary (registry, in English)

Characterize and trace innovative nutraceuticals based on microencapsulated resveratrol and Cynara cardunculus extract, using preclinical models such as organotypic tissue slices and tumoroids created from tumor fragments derived from patients with non-small cell lung cancer. This will enable the development of combination therapies to increase the efficacy of immunotherapy in NSCLC and reduce side effects that lead to treatment discontinuation. The market implementation of these products may offer unique advantages, including increased clinical efficacy, improved tolerability of immune checkpoint inhibitors, reduced healthcare costs, improved quality of life for patients and their families, traceability of naturally derived products, and environmental sustainability.

Status (registry)
Recruiting
Study type
Observational
Enrollment
5 (estimated)
First submitted
18 Nov 2025
Start date
24 Jul 2025
Primary completion date
24 Apr 2026
Lead sponsor
Regina Elena Cancer Institute
Diseases
Lung cancer
NCT number
NCT07629375

What you commit to

  • Study type: Observational
  • Planned participants: 5
  • From 24 Jul 2025 to the primary completion date, 24 Apr 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous systemic treatments.

Other illness

  • Previous malignancies;

Who the study is looking for

  • Patients over 18 years of age;
  • Patients diagnosed with resectable NSCLC who will undergo curative surgery;
  • Patients who give written informed consent (study participation and data processing).

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
IRCCS National Cancer Institute "Regina Elena"
Coordinator of this site? Confirm its status
RomeItalyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.