NCT07634926Not yet recruiting
Early Time-Restricted Eating for Cardiovascular Health
Aligning Clocks: Time-Restricted Eating to Improve Cardiovascular Health in Hypertensive Older Adults Who Skip Breakfast
Source: ClinicalTrials.gov · Last updated 28 Sept 2026
Brief summary (registry, in English)
This study will examine whether eating earlier in the day within a consistent 8-hour eating window can improve heart and blood vessel health in older adults with high blood pressure who often skip breakfast. Participants will be randomly assigned to either follow an early time-restricted eating schedule or continue their usual eating habits for 12 weeks. Researchers will measure blood pressure, blood vessel function, and biological markers related to the body's internal clock and oxidative stress to better understand how meal timing affects cardiovascular health.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 36 (estimated)
- First submitted
- 3 Jun 2026
- Start date
- 30 Nov 2026
- Primary completion date
- 31 Mar 2029
- Lead sponsor
- University of Alabama at Birmingham
- Diseases
- High blood pressure
- NCT number
- NCT07634926
What you commit to
- Study type: Interventional
- Planned participants: 36
- From 30 Nov 2026 to the primary completion date, 31 Mar 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Rheumatoid arthritis, Parkinson's disease or currently on dialysis
- Taking medications that preclude fasting for 16 hours (e.g. must be taken with food at least 12 hours apart)
Other illness
- Resting heart rate of \>120 beats/minute, systolic BP \>180 and/or diastolic BP \>100 mmHg
- Have been diagnosed with diabetes
- On insulin or diabetes medication
- Unstable angina, heart attack or stroke in the past 3 months
- Continuous use of supplemental oxygen to manage a chronic pulmonary condition or heart failure
- Current diagnosis of a major psychiatric condition that would impair study participation
- Severe gastrointestinal disease, major gastrointestinal surgery, or active gallstone disease
- Active treatment for cancer in the past year
- Diagnosed cognitive impairment
- Any condition that in the opinion of the investigator would impair ability to participate in the trial
Other
- Fasting \>13 hours per day
- Actively trying to lose weight by participating in formal weight loss program or significantly restricting calorie intake
- Have lost ≥ 10 pounds in last 3 months
- Self-reported exercise over 90 min/week
- Unable to wake up at a regular time between 6-9 am
- Perform overnight shift work more than 1day/week on average
- Pregnant or breastfeeding
- Unable to fast for 16 hours.
Who the study is looking for
- Men and women ≥ 60 years old
- Average office systolic BP ≥130 mmHg5
- Self-reported skipping breakfast for at least 3 days in the past 7 days
- Identified as having a morning or evening chronotype according to the Morningness-Eveningness Questionnaire68
- Stable health history over the past 2 months
- Stable medication history over the past 2 months, as recommended by the primary provider
- Willing and able to provide informed consent.
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Alabama at Birmingham Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.