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NCT07635043Not yet recruitingPhase 4

Efficacy of Topical Tapinarof Versus Betamethasone in the Treatment of Plaque Psoriasis

Source: ClinicalTrials.gov · Last updated 9 Jun 2026

Brief summary (registry, in English)

To assess the effectiveness of topical tapinarof to topical betamethasone in patients with mild to moderate plaque psoriasis presenting to tertiary care hospital in Islamabad

Status (registry)
Not yet recruiting
Phase (registry)
Phase 4
Study type
Interventional
Enrollment
120 (estimated)
First submitted
3 Jun 2026
Start date
1 Aug 2026
Primary completion date
31 Oct 2026
Lead sponsor
Pakistan Institute of Medical Sciences
Diseases
Psoriasis
NCT number
NCT07635043

What you commit to

  • Study type: Interventional · Phase 4
  • Planned participants: 120
  • From 1 Aug 2026 to the primary completion date, 31 Oct 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Severe psoriasis (BSA \>20% or requiring systemic therapy)
  • Concurrent dermatological conditions that may interfere with assessment e.g fungal infections,atopic dermatitis
  • Use of systemic immunosuppressants (methotrexate, cyclosporine, biologics ) or phototherapy within 4 weeks before enrollment
  • Use of powerful topical corticosteroids within two weeks previously

Other illness

  • Known hypersensitivity to Tapinarof or any of its excipients
  • History of malignancy or current active infection
  • Known hypersensitivity to betamethasone or Tapinarof

Other

  • Pregnant and lactating mothers

Who the study is looking for

  • Age 18 years-65 years
  • Clinically diagnosed plaque psoriasis involving body surface area ( BSA) of 2-20% (mild to moderate severity)
  • Disease duration of at least 6 months
  • Willing and able to provide written informed consent
  • Not currently using any other topical and systematic psoriasis therapy, or willing to undergo a washout period (2 weeks for topical therapies)

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Pakistan institute of medical sciences(PIMS)
Coordinator of this site? Confirm its status
IslamabadPakistanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.