NCT07635082CompletedPhase 2
Extended Letrozole Protocol Versus Letrozole Plus Inositol for Induction of Ovulation in Letrozole Resistant PCOS Women
Source: ClinicalTrials.gov · Last updated 9 Jun 2026
Brief summary (registry, in English)
Extended letrozole protocol versus letrozole plus Inositol for Induction of ovulation in letrozole resistant PCOS Women
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 200 (actual)
- First submitted
- 18 May 2026
- Start date
- Feb 2024
- Primary completion date
- Jun 2025
- Lead sponsor
- Eman Basuni Ebrahim Mowad
- NCT number
- NCT07635082
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 200
- From Feb 2024 to the primary completion date, Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of insulin-sensitizing medications (e.g., metformin) during the study period.
Other illness
- Diabetes mellitus.
- Chronic liver disease.
- Chronic kidney disease.
- Contraindications or hypersensitivity to inositol or letrozole.
Other
- Thyroid dysfunction.
- Hyperprolactinemia.
- Congenital adrenal hyperplasia.
- Adrenal causes of hyperandrogenism.
- Contraindications to pregnancy.
Who the study is looking for
- Women diagnosed with polycystic ovary syndrome (PCOS) according to the Rotterdam criteria.
- Letrozole-resistant PCOS patients who failed to ovulate after receiving letrozole 5 mg daily for 5 days for three consecutive cycles.
- Age 18 to 35 years.
- Body mass index (BMI) ≤ 30 kg/m².
- Normal uterine cavity and patent fallopian tubes confirmed by hysterosalpingography (HSG) and/or laparoscopy.
- Partner with normal semen analysis.
- Willing and able to provide informed consent.
Age in the registry: 18 years to 35 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kafrelsheikh University Hospital Coordinator of this site? Confirm its status | Kafr ash Shaykh | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.