NCT07637214Completed
A Real-world Study: Analysis of the Efficacy of Antiviral Therapy in CHB Patients Over 30 Years Old, HBV DNA Positive and ALT Normal
Curative Effect Analysis of Antiviral Therapy in CHB Patients Over 30 Years Old With HBV DNA Positive and Normal ALT
Source: ClinicalTrials.gov · Last updated 9 Jun 2026
Brief summary (registry, in English)
This is a prospective observational study of CHB patients who have not received antiviral treatment but HBV DNA are positive.Investigators aim to explore the antiviral effect and influencing factors of patients over 30 years old with normal ALT level after receiving antiviral treatment.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 250 (actual)
- First submitted
- 13 Apr 2026
- Start date
- 13 Mar 2023
- Primary completion date
- 13 Mar 2024
- Lead sponsor
- Tongji Hospital
- Diseases
- Hepatitis B
- NCT number
- NCT07637214
What you commit to
- Study type: Observational
- Participants enrolled: 250
- From 13 Mar 2023 to the primary completion date, 13 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous history of liver cancer, organ transplantation and alcoholism (male ≥30 g/d, female ≥20 g/d);
Other illness
- Patients with compensated/decompensated cirrhosis and liver cancer have been diagnosed by imaging or other indicators;
- HCV, HIV, EB virus/cytomegalovirus infection, schistosomiasis liver disease, drug-induced liver injury, autoimmune hepatitis and alcoholic liver disease;
- Combined with other major diseases.
Lab values
- Insufficient follow-up time and imperfect clinical/laboratory informations;
Other
- pregnancy status;
- Use immunosuppressants ;
Who the study is looking for
- CHB patients over 30 years old ；
- HBV DNA \>20IU/ml and ALT level ≤40U/L；
- All of them have never received any antiviral treatment(including NAs and interferon-α）。
Age in the registry: 30 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tongji Hospital,Wuhan,Hubei Coordinator of this site? Confirm its status | Wuhan | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.