NCT07639021Active, not recruitingPhase 2
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
Evaluation of Different Dose Escalation Regimens for NNC0662-0419 in Participants With Obesity
Source: ClinicalTrials.gov · Last updated 16 Sept 2026
Brief summary (registry, in English)
The purpose of the study is to find out if NNC0662-0419 is safe and effective for treating participants living with obesity.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 233 (actual)
- First submitted
- 5 Jun 2026
- Start date
- 9 Jun 2026
- Primary completion date
- 14 Jun 2027
- Lead sponsor
- Novo Nordisk A/S
- Diseases
- Obesity
- NCT number
- NCT07639021
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 233
- From 9 Jun 2026 to the primary completion date, 14 Jun 2027
- 25 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with any medication prescribed for the indication of obesity or weight management (e.g. glucagon-like-peptide-1 (GLP-1) receptor agonists (RA), dual GLP-1/gastric inhibitory peptide (GIP) RAs (or any other GLP-1 based treatment) or amylin analogues)) within 90 days before screening.
Other illness
- Known or suspected hypersensitivity to study intervention(s) or related products.
- History of type 1 or type 2 diabetes mellitus.
Lab values
- Glycated haemoglobin (HbA1c) ≥ 6.5% (48 Millimoles per mole \[mmol/mol\]) as measured by the central laboratory at screening.
Who the study is looking for
- Male or female (sex assigned at birth, inclusive of all gender identities).
- Age 18 years or above at the time of signing the informed consent.
- Body mass index (BMI) greater than or equal to (≥) 30.0 kilogram per square meter (kg/m\^2) at screening.
- Participant must have a desire and be committed to lose at least 25 percentage (%) of their body weight from randomisation.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (25)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Isis Clinical Res. Ctr P.S.C. Coordinator of this site? Confirm its status | Guaynabo | Puerto Rico | Unknown status |
| Holston Medical Group_Bristol Coordinator of this site? Confirm its status | Bristol | United States | Unknown status |
| Great Lakes Clinical Trials Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| Cedar Crosse Research Center Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| StudyMetrix Research, LLC Coordinator of this site? Confirm its status | City of Saint Peters | United States | Unknown status |
| FDRC Coordinator of this site? Confirm its status | Costa Mesa | United States | Unknown status |
| Clinical Res Collaborative Coordinator of this site? Confirm its status | Cumberland | United States | Unknown status |
| Encore Medical Research LLC Coordinator of this site? Confirm its status | Hollywood | United States | Unknown status |
| PlanIt Research, PLLC Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| Midwest Inst For Clin Res Coordinator of this site? Confirm its status | Indianapolis | United States | Unknown status |
| Holston Medical Group. Coordinator of this site? Confirm its status | Kingsport | United States | Unknown status |
| Los Angeles Institute for Metabolic Research Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
| L-MARC Research Center Coordinator of this site? Confirm its status | Louisville | United States | Unknown status |
| South Broward Research LLC Coordinator of this site? Confirm its status | Miramar | United States | Unknown status |
| Chambliss Clinical Trials, LLC Coordinator of this site? Confirm its status | Montgomery | United States | Unknown status |
| Clinical Research Associates Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| West Orange Endocrinology Coordinator of this site? Confirm its status | Ocoee | United States | Unknown status |
| UPA Ctr Weight and Eating Dis Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Rainier Clin Res Ctr Inc Coordinator of this site? Confirm its status | Renton | United States | Unknown status |
| National Clin Res Inc. Coordinator of this site? Confirm its status | Richmond | United States | Unknown status |
| Endo And Metab Cons Coordinator of this site? Confirm its status | Rockville | United States | Unknown status |
| Pinnacle Clinical Research Coordinator of this site? Confirm its status | San Antonio | United States | Unknown status |
| Family Practice Center of Wadsworth Inc. Coordinator of this site? Confirm its status | Wadsworth | United States | Unknown status |
| Great Lakes Medical Research Coordinator of this site? Confirm its status | Westfield | United States | Unknown status |
| KDCILM, LLC & Accellacare US, Inc. Coordinator of this site? Confirm its status | Wilmington | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.