NCT07641803Completed
Mirror Therapy Versus Action Observation Therapy on Upper Limb Motor Function, Functional Independence, and Quality Oflife Among Chronic Stroke Patients
Source: ClinicalTrials.gov · Last updated 11 Jun 2026
Brief summary (registry, in English)
This randomized controlled trial aims to compare the effects of Mirror Therapy (MT) and Action Observation Therapy (AOT) on upper limb motor function, functional independence, and health-related quality of life in individuals with chronic stroke. Stroke-related upper limb impairment remains a major cause of long-term disability and reduced independence. Both MT and AOT are neurocognitive rehabilitation approaches based on activation of the mirror neuron system and promotion of neuroplasticity. Eligible participants with chronic stroke will be randomly allocated to either a Mirror Therapy group or an Action Observation Therapy group and will receive supervised interventions in addition to standard physiotherapy. Outcomes will be assessed using the Motor Evaluation Scale for Upper Extremity in Stroke Patients (MESUPES), Fugl-Meyer Assessment for Upper Extremity (FMA-UE), and Short Form-36 Health Survey (SF-36). The study seeks to determine the comparative effectiveness of these interventions for improving upper limb function, functional independence, and quality of life among chronic stroke survivors.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 76 (actual)
- First submitted
- 6 Jun 2026
- Start date
- 3 Feb 2025
- Primary completion date
- 19 Mar 2026
- Lead sponsor
- University of Lahore
- Diseases
- Stroke
- NCT number
- NCT07641803
What you commit to
- Study type: Interventional
- Participants enrolled: 76
- From 3 Feb 2025 to the primary completion date, 19 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of severe visual or perceptual deficits (e.g., neglect, hemianopia).
- Uncontrolled epilepsy or active psychiatric disorders.
Other
- Severe cognitive or communication impairments prevent task understanding.
- Presence of severe upper limb spasticity or contractures.
- Participation in other upper limb rehabilitation programs during the study period.
Who the study is looking for
- Individuals diagnosed with chronic stroke (≥6 months post-stroke).
- Patients with stroke affecting either the left or right upper limb will be included.
- Mild-to-moderate upper limb motor impairment (Fugl-Meyer Upper Extremity Score between 19-55).
- Ability to follow verbal and visual instructions.
- Medically stable with no active comorbidities affecting rehabilitation (Tang et al., 2024).
Age in the registry: 45 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The University of Lahore Teaching Hospital Coordinator of this site? Confirm its status | Lahore | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.