NCT07643415Recruiting
Spinal Versus General Anesthesia in Open Simple Prostatectomy
Effect of Spinal Versus General Anesthesia on Postoperative Bleeding in Patients Undergoing Open Simple Prostatectomy: A Prospective Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 16 Jun 2026
Brief summary (registry, in English)
Open simple prostatectomy is still performed for selected patients with benign prostatic hyperplasia, particularly in cases with large prostate volume. Postoperative bleeding, hematuria, clot retention, and transfusion requirement are clinically important complications after this procedure. This prospective randomized controlled trial will compare the effects of spinal anesthesia and general anesthesia on postoperative bleeding in patients undergoing open simple prostatectomy. Participants will be randomized into two groups: spinal anesthesia or general anesthesia. Tranexamic acid or any additional hemostatic agent will not be used. Postoperative bleeding will be assessed using hemoglobin and hematocrit changes, transfusion requirement, hematuria, clot retention, need for bladder irrigation, and bleeding-related reintervention. The study aims to determine whether spinal anesthesia is associated with reduced postoperative bleeding compared with general anesthesia in open simple prostatectomy.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 8 Jun 2026
- Start date
- 29 Apr 2026
- Primary completion date
- 15 Aug 2026
- Lead sponsor
- Hitit University
- NCT number
- NCT07643415
What you commit to
- Study type: Interventional
- Planned participants: 80
- From 29 Apr 2026 to the primary completion date, 15 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Emergency surgery.
- Ongoing anticoagulant or antiplatelet therapy that cannot be discontinued according to institutional protocols.
Other illness
- Patients scheduled for radical prostatectomy due to prostate cancer.
- Known coagulation disorders or clinically significant thrombocytopenia.
Other
- Refusal or inability to provide informed consent.
- Contraindication to spinal anesthesia.
- Participation in another interventional clinical trial that may affect study outcomes.
- Administration of tranexamic acid or any additional hemostatic agent during the perioperative period.
Who the study is looking for
- Male patients aged 18 years or older.
- Diagnosis of benign prostatic hyperplasia (BPH).
- Scheduled to undergo open simple prostatectomy.
- American Society of Anesthesiologists (ASA) physical status I-III.
- Ability to provide written informed consent.
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hitit University Coordinator of this site? Confirm its status | Çorum | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.