NCT07644806Recruiting
Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction
Olive Oil Supplementation to Enhance Exercise Tolerance in Cardiac Rehabilitation in Patients With Heart Failure With Reduced Ejection Fraction: The OLEA-HF Study
Source: ClinicalTrials.gov · Last updated 16 Oct 2026
Brief summary (registry, in English)
The OLEA-HF study aims to explore whether daily supplementation of extra-virgin olive oil (EVOO) for 12 weeks during participation in a cardiac rehabilitation program (standard of care) is feasible in patients with heart failure with reduced ejection fraction (HFrEF). The investigators will also determine the effects of EVOO on functional capacity and quality of life.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 4 Jun 2026
- Start date
- 1 Jul 2026
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Old Dominion University
- Diseases
- Heart failure
- NCT number
- NCT07644806
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 Jul 2026 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Co-morbidity expected to limit survival (e.g., terminal illness).
- End-stage renal disease.
- Known allergy or sensitivity to olive oil or its components.
Other
- Unstable fluid overload.
- Current pregnancy (self-disclose).
- Habitual use of EVOO greater than 4 tablespoons per day.
- Unwillingness or inability to incorporate EVOO or dietary recommendations.
Who the study is looking for
- Diagnosed with HFrEF with left ventricular ejection fraction ≤35 %.
- Referred to and enrolled in the standard cardiac rehabilitation program at Sentara Cardiac Rehabilitation Center, but has not yet initiated/started cardiac rehabilitation (i.e., has not attended the first cardiac rehab session).
- Able and willing to comply with study procedures and provide informed consent.
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Strelitz Diabetes Center (Williams Hall) Coordinator of this site? Confirm its status | Norfolk | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.