NCT07647939Not yet recruiting
Exclusion of Left Atrial Appendage Thrombus in Emergency Department Patients With Atrial Fibrillation Undergoing CT to Assess for Pulmonary Embolus: A Feasibility Study
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
This study aims to investigate whether a quick, additional CT scan of the heart, performed immediately after a standard CT scan for pulmonary embolism, can effectively detect blood clots in the left atrial appendage (LAA) in patients with atrial fibrillation. Detecting these clots is crucial before certain heart procedures to prevent stroke. Currently, a different, more involved procedure (Transesophageal Echocardiography - TEE) is often used. This study will assess if this additional CT scan is feasible, meaning if it can provide clear enough images to identify LAA clots without needing more contrast dye. The study will involve 60 patients, half receiving an "ungated" CT scan and the other half a "gated" CT scan (timed with their heart rhythm). The results of these scans will not be used for immediate patient care during the study, but rather to evaluate the CT scan technique itself. There is no direct benefit to participants, but the information gained could lead to faster diagnosis and reduced unnecessary testing for future patients.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 16 Mar 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 30 Apr 2027
- Lead sponsor
- Northwell Health
- Diseases
- Atrial fibrillation
- NCT number
- NCT07647939
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 1 Nov 2026 to the primary completion date, 30 Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Stroke like symptoms
- Heart rate \<40 or \> 120 bpm (inclusive) or 3rd degree heart block
Other
- Inability to personally give informed consent
- Pregnant or breastfeeding individuals
- ECG criteria for ischemia or infarction
- Unable to lie flat for at least 10 minutes
- Unable to follow simple commands
- Northwell Health Employees.
- Non-English-speaking patients
Who the study is looking for
- Patients above 18 years of age years deemed candidates for CT angiography for pulmonary embolism by the primary team on clinical grounds and noted to be in atrial fibrillation at the time.
- Room air oxygen saturation above 92%
- Systolic blood pressure above 100 mm Hg
- Respiratory rate less than 24 breaths/min
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| North Shore University Hospital Coordinator of this site? Confirm its status | Manhasset | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.