NCT07648498Recruiting
Feasibility of a Community-Integrated Isometric Handgrip Exercise Program and Its Preliminary Effects on Blood Pressure and Cognitive Function in Older Adults
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate whether a short, supervised isometric handgrip exercise program is feasible and acceptable for older adults with elevated blood pressure or hypertension. It will also explore whether this type of exercise may improve blood pressure and cognitive function. The main questions it aims to answer are: * Is this handgrip exercise program practical and acceptable for older adults to participate in within a community exercise setting? * Does participation in the program lead to changes in blood pressure and cognitive function? Researchers will compare two handgrip devices to determine whether the method of delivering the exercise influences feasibility and outcomes. Participants will: * Be randomly assigned to use one of two handgrip devices. * Complete supervised exercise sessions twice per week for 4 weeks. * Perform brief handgrip contractions at a set intensity during each session. * Complete blood pressure and cognitive assessments before and after the program.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 21 Apr 2026
- Start date
- 18 Aug 2026
- Primary completion date
- 15 Apr 2027
- Lead sponsor
- McMaster University
- Diseases
- High blood pressure
- NCT number
- NCT07648498
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 18 Aug 2026 to the primary completion date, 15 Apr 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current or prior participation in chronic isometric exercise
- Changes to the type and/or dose of blood pressure medications within 3 months of starting the study.
Other illness
- Unstable angina.
- Uncontrolled hypertension
- Uncontrolled heart failure and/or arrhythmias
- Recent myocardial infarction or electrocardiography changes
- Complete heart block
- Carpal tunnel syndrome
Other
- Arthritis that may be aggravated by handgrip exercise
Who the study is looking for
- 65 years of age or older
- Currently attending the Physical Activity Centre of Excellence at McMaster University
- English speaking
- Diagnosed with hypertension or elevated blood pressure
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| NeuroFit Lab, Ivor Wynne Centre, McMaster University Coordinator of this site? Confirm its status | Hamilton | Canada | Recruiting |
| Physical Activity Centre of Excellence, Ivor Wynne Centre, McMaster University Coordinator of this site? Confirm its status | Hamilton | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.