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NCT07649148Not yet recruiting

Dietary Tracking in Heart Failure

Dietary Optimization Through Tracking and Integrated Evaluation

Source: ClinicalTrials.gov · Last updated 28 Sept 2026

Brief summary (registry, in English)

Emerging evidence links ultra processed foods (UPFs) to adverse cardiovascular outcomes. UPFs are often high in sodium, unhealthy fats and added sugars, while being low in essential nutrients and fiber. UPFs contribute to systemic inflammation, fluid retention, and metabolic dysfunction-key drivers of HF and kidney disease progression. Traditional dietary counseling often lacks specificity around food processing levels. Furthermore, the majority of nutrition studies relied on extensive self-reported dietary recall food frequency questionnaires (FFQ) that are subjective, often labor intensive, and difficult to implement practically in the clinical setting. As such, researchers have developed metabolite scores from blood and urine samples to help quantify UPF consumption, which has the promise to better guide dietary counseling and track process. Therefore, the aim of this study is to evaluate the feasibility and physiological impact of a structured UPF-reduction dietary intervention in patients with HF, leveraging both digital dietary tools (Cronometer) and biomarker assessments.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
60 (estimated)
First submitted
9 Jun 2026
Start date
1 Dec 2026
Primary completion date
31 Dec 2036
Lead sponsor
The Cleveland Clinic
NCT number
NCT07649148

What you commit to

  • Study type: Observational
  • Planned participants: 60
  • From 1 Dec 2026 to the primary completion date, 31 Dec 2036
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of heart transplant or LVAD implant

Lab values

  • eGFR \<30 ml/kg/1.73m2

Other

  • Unable or unwilling to follow dietary coaching for UPF reduction

Who the study is looking for

  • Adults (≥18 years) with NYHA Class II-III HF
  • Able to use Cronometer to track dietary intake and able to prepare food at home independently (able to modify dietary intake)

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Cleveland Clinic - Main Campus
Coordinator of this site? Confirm its status
ClevelandUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.