NCT07649681Recruiting
Gustabor Phase 2 - Treating Taste Changes During Cancer Therapy: A Randomized Study Evaluating an AI- Based Nutrition Intervention
Source: ClinicalTrials.gov · Last updated 20 Aug 2026
Brief summary (registry, in English)
The study investigates taste disorders that commonly occur during or after cancer treatment, often leading to issues such as malnutrition and treatment discontinuation. Although many non-pharmacological recommendations exist, it is unclear which methods are suitable for which individuals. This randomized study aims to compare the effectiveness of individualized dietary recommendations (Gustabor group) with the current standard of care -general recommendations (Control group). Participants will undergo an objective assessment of taste disorders using taste strips and questionnaires. Based on the results, the Gustabor group will receive both general and specific dietary suggestions. These will be accomapnied by AI-generated recipe suggestions tailored to specific taste disorders (e.g., more cold foods in cases of metallic taste). The control group will receive the current standard: a flyer containing general dietary advice for oncology patients previously shown to be beneficial for managing taste alterations. The primary endpoint is the PG-SGA score within 12 weeks of inclusion.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 198 (estimated)
- First submitted
- 10 Jun 2026
- Start date
- 24 Jul 2026
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Wuerzburg University Hospital
- Diseases
- Melanoma, Multiple myeloma
- NCT number
- NCT07649681
What you commit to
- Study type: Interventional
- Planned participants: 198
- From 24 Jul 2026 to the primary completion date, 31 Dec 2026
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Taste disorder explained by other causes (e.g. existing before therapy or COVID disease)
Other
- Pregnancy
- Placement in an inpatient care facility
Who the study is looking for
- Age ≥ 18
- Suffering from one of the following tumor entities: Multiple myeloma, melanoma, urogenital cancer or malignant tumor of the gastrointestinal tract
- Mainly oral nutrition
- Subjectively perceived tumor therapy-related taste disorder
- At least two clinical presentations planned within 12 weeks with a minimum interval of three weeks
- Ability to participate in nutritional intervention, including use of the online portal and implementation of recipe suggestions (e.g. resources and access to a kitchen), either independently or with third-party support (e.g. by relatives, outpatient care services).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universitätsklinikum Augsburg Coordinator of this site? Confirm its status | Augsburg | Germany | Not yet recruiting |
| Universitätsklinikum Erlangen Coordinator of this site? Confirm its status | Erlangen | Germany | Recruiting |
| Klinikum der Technischen Universität München (TUM Klinikum) Coordinator of this site? Confirm its status | München | Germany | Not yet recruiting |
| LMU Klinikum Krebszentrum - CCC MünchenLMU - Comprehensive Cancer Center Coordinator of this site? Confirm its status | München | Germany | Recruiting |
| Universitätsklinikum Regensburg Coordinator of this site? Confirm its status | Regensburg | Germany | Not yet recruiting |
| Universitätsklinikum Würzburg Coordinator of this site? Confirm its status | Würzburg | Germany | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.