Fact CheckerSign in

NCT07652476Not yet recruiting

Neurocognitive Assessment in Long-Term Survivors of Lymphoma

Neurocognitive Assessment in Long-Term Survivors of Lymphoma: An Observational Study by the Fondazione Italiana Linfomi (FIL)

Source: ClinicalTrials.gov · Last updated 22 Jun 2026

Brief summary (registry, in English)

This is an observational, multicenter, prospective cohort study including patients treated for lymphoma in Italian real-life. Patients eligible for the enrollment in the study will be consecutively included in Italian FIL centers. Patients will be evaluated once during regular follow-up, in the absence of clinical or radiologic signs of disease relapse. The assessment of neurocognitive functioning will be performed through a panel of tests, both self-administered and individually administered (about 1 hour). The administration of these neuropsychological tests should be done according to a standardized and predefined order. If available, according to local practice, a neuropsychologist may be involved in test administration and in the evaluation of the results. Based on its observational nature, no treatment change or modification or additional exams or visits will be required because of being enrolled in this study.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
11 Jun 2026
Start date
Sept 2026
Primary completion date
Mar 2028
Lead sponsor
Fondazione Italiana Linfomi - ETS
NCT number
NCT07652476

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From Sept 2026 to the primary completion date, Mar 2028
  • 7 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients that received brain/neuroaxis radiotherapy.

Other illness

  • Patients with CNS disease localization.
  • Pre-existing severe psychiatric or neurologic comorbidities influencing neurocognitive assessment.

Who the study is looking for

  • Patients with previous diagnosis of classic Hodgkin Lymphoma (cHL) or Diffuse Large B Cell Lymphoma (DLBCL) or Primary Mediastinal B Cell Lymphoma (PMBCL).
  • Patients in complete remission after first line anthracycline containing regimen (ABVD, BV-AVD, BEACOPP, R-CHOP, Pola-R-CHP o R-DA-EPOCH) +/- radiotherapy.
  • Age ≥ 25 and ≤ 55 at enrollment.
  • Patients between third and fifth year of follow-up after the end of the first line treatment.
  • Absence of signs or symptoms of disease relapse.

Age in the registry: 25 years to 55 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (7)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Clinica di Ematologia, AOU Ospedali Riuniti
Coordinator of this site? Confirm its status
AnconaItalyUnknown status
Divisione di Oncologia e dei Tumori immuno-correlati - IRCCS Centro di Riferimento Oncologico di Aviano
Coordinator of this site? Confirm its status
AvianoItalyUnknown status
U.O.C Ematologia - IRCCS Istituto Tumori Giovanni Paolo II
Coordinator of this site? Confirm its status
BariItalyUnknown status
U.O.C. Ematologia Ospedale Civile di Legnano - ASST Ovest Milanese
Coordinator of this site? Confirm its status
LegnanoItalyUnknown status
Ematologia - Ospedale Maggiore Policlinico - Fondazione IRCCS Ca Granda
Coordinator of this site? Confirm its status
MilanItalyUnknown status
SC Ematologia - ASST Grande Ospedale Metropolitano Niguarda
Coordinator of this site? Confirm its status
MilanItalyUnknown status
Ematologia AOU Policlinico Giaccone
Coordinator of this site? Confirm its status
PalermoItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.