NCT07652476Not yet recruiting
Neurocognitive Assessment in Long-Term Survivors of Lymphoma
Neurocognitive Assessment in Long-Term Survivors of Lymphoma: An Observational Study by the Fondazione Italiana Linfomi (FIL)
Source: ClinicalTrials.gov · Last updated 22 Jun 2026
Brief summary (registry, in English)
This is an observational, multicenter, prospective cohort study including patients treated for lymphoma in Italian real-life. Patients eligible for the enrollment in the study will be consecutively included in Italian FIL centers. Patients will be evaluated once during regular follow-up, in the absence of clinical or radiologic signs of disease relapse. The assessment of neurocognitive functioning will be performed through a panel of tests, both self-administered and individually administered (about 1 hour). The administration of these neuropsychological tests should be done according to a standardized and predefined order. If available, according to local practice, a neuropsychologist may be involved in test administration and in the evaluation of the results. Based on its observational nature, no treatment change or modification or additional exams or visits will be required because of being enrolled in this study.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 11 Jun 2026
- Start date
- Sept 2026
- Primary completion date
- Mar 2028
- Lead sponsor
- Fondazione Italiana Linfomi - ETS
- Diseases
- Diffuse large B-cell lymphoma
- NCT number
- NCT07652476
What you commit to
- Study type: Observational
- Planned participants: 100
- From Sept 2026 to the primary completion date, Mar 2028
- 7 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients that received brain/neuroaxis radiotherapy.
Other illness
- Patients with CNS disease localization.
- Pre-existing severe psychiatric or neurologic comorbidities influencing neurocognitive assessment.
Who the study is looking for
- Patients with previous diagnosis of classic Hodgkin Lymphoma (cHL) or Diffuse Large B Cell Lymphoma (DLBCL) or Primary Mediastinal B Cell Lymphoma (PMBCL).
- Patients in complete remission after first line anthracycline containing regimen (ABVD, BV-AVD, BEACOPP, R-CHOP, Pola-R-CHP o R-DA-EPOCH) +/- radiotherapy.
- Age ≥ 25 and ≤ 55 at enrollment.
- Patients between third and fifth year of follow-up after the end of the first line treatment.
- Absence of signs or symptoms of disease relapse.
Age in the registry: 25 years to 55 years · Sex: All · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinica di Ematologia, AOU Ospedali Riuniti Coordinator of this site? Confirm its status | Ancona | Italy | Unknown status |
| Divisione di Oncologia e dei Tumori immuno-correlati - IRCCS Centro di Riferimento Oncologico di Aviano Coordinator of this site? Confirm its status | Aviano | Italy | Unknown status |
| U.O.C Ematologia - IRCCS Istituto Tumori Giovanni Paolo II Coordinator of this site? Confirm its status | Bari | Italy | Unknown status |
| U.O.C. Ematologia Ospedale Civile di Legnano - ASST Ovest Milanese Coordinator of this site? Confirm its status | Legnano | Italy | Unknown status |
| Ematologia - Ospedale Maggiore Policlinico - Fondazione IRCCS Ca Granda Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| SC Ematologia - ASST Grande Ospedale Metropolitano Niguarda Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| Ematologia AOU Policlinico Giaccone Coordinator of this site? Confirm its status | Palermo | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.