NCT07653269Recruiting
Predicting Risk of Progression of Early to Late AMD in the Aging Eye Through Imaging and Multimodal Evaluation
Predicting Risk of Progression of Early to Late AMD in the Aging Eye Through Imaging and Multimodal Evaluation - PRIME Study
Source: ClinicalTrials.gov · Last updated 18 Jun 2026
Brief summary (registry, in English)
The purpose of this research study is to evaluate a new screening procedure for the early detection and monitoring of Age-related Macular Degeneration (AMD) in community settings and community hospital settings, to identify associated risk factors, and develop personalized monitoring strategies for at-risk individuals throughout the 5 years follow up period, which will allow us to establish prevalence, natural history of progression of early AMD in the community.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1500 (estimated)
- First submitted
- 11 Jun 2026
- Start date
- 18 Oct 2025
- Primary completion date
- 31 Jul 2029
- Lead sponsor
- Singapore National Eye Centre
- Diseases
- Macular degeneration
- NCT number
- NCT07653269
What you commit to
- Study type: Observational
- Planned participants: 1500
- From 18 Oct 2025 to the primary completion date, 31 Jul 2029
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Systemic disorders that preclude reliable clinical examination or multimodal imaging
- Poor compliance or severe mental illness that hinders participation
Other
- Persons who are unable to give informed consent
Who the study is looking for
- Adults aged 55 years or older
- No severe systemic illnesses that prevent study participation
- Willing and able to undergo protocol-required procedures for both eyes
- Willing and able to provide written informed consent
Age in the registry: 55 years to - · Sex: All
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Singapore National Eye Centre/Singapore Eye Research Institute Coordinator of this site? Confirm its status | Singapore | Singapore | Recruiting |
| Outram Community Hospital Coordinator of this site? Confirm its status | Singapore | Singapore | Recruiting |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.