NCT07654647Recruiting
Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.
Evaluation of the Effectiveness of Patient-Specific 3D-Printed Titanium Facial Implants in the Reconstruction and Aesthetic Correction of Facial Defects: A Clinical Study
Source: ClinicalTrials.gov · Last updated 17 Jun 2026
Brief summary (registry, in English)
This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects. The study will include patients presenting with congenital, traumatic, or post-surgical facial deformities requiring reconstructive intervention. Eligible participants will undergo preoperative clinical assessment and radiological imaging to design customized implants using computer-aided design (CAD) and 3D printing technology. The implants will be fabricated from medical-grade titanium and surgically placed according to standardized maxillofacial reconstructive protocols. Postoperative follow-up will assess functional outcomes, implant stability, complication rates, and aesthetic improvement over a defined observation period. Outcome evaluation will include clinical examination and patient-reported satisfaction measures. The objective of this study is to determine whether patient-specific 3D-printed titanium implants provide reliable functional restoration and improved aesthetic outcomes in facial reconstruction compared to conventional reconstructive techniques.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 5 Jun 2026
- Start date
- Apr 2026
- Primary completion date
- Nov 2026
- Lead sponsor
- Latakia University
- Diseases
- Head and neck cancer
- NCT number
- NCT07654647
What you commit to
- Study type: Interventional
- Planned participants: 30
- From Apr 2026 to the primary completion date, Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of radiotherapy within 12 months prior to enrollment.
Other illness
- Uncontrolled diabetes mellitus.
Age
- Age below 18 years.
Other
- Active pathological lesions at the time of enrollment.
- Chronic untreated vitamin D deficiency.
- Inability or unwillingness to comply with follow-up requirements.
Who the study is looking for
- Age 18 years or older.
- Presence of facial bone defects resulting from cystic or tumoral osteolytic lesions.
- Acquired or congenital facial deformities associated with bony defects or facial asymmetry.
- Patients requiring patient-specific 3D-printed titanium implants for maxillofacial reconstruction.
- Aesthetic indications requiring custom facial implant design, including microgenia (chin retrusion).
- Ability to provide written informed consent.
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ahmad Fayez Ahmad Coordinator of this site? Confirm its status | Latakia | Syria | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.