A Personalized Mobile Application Providing Temperature-Related Health Risk Warnings and Protective Recommendations for Patients With Chronic Obstructive Pulmonary Disease

Criteria the registry did not label

• Hospital inclusion criteria:
• Tertiary hospitals;
• Hospitals with respiratory wards that admit patients with COPD;
• Hospitals with a well-established electronic health record system and follow-up capability;
• Hospitals able to assign a study coordinator.
  • Patient inclusion criteria:
• Age \>=40 years and \<=80 years, with no restriction on sex;
• Patients with stable chronic obstructive pulmonary disease;
• At least 1 severe acute exacerbation requiring hospitalization, or at least 2 moderate acute exacerbations requiring outpatient or emergency care, within the previous year;
• Local permanent residents with a duration of residence \>=6 months;
• Patients who voluntarily agree to participate, are expected to have good adherence, are able to sign informed consent;
• Patients who own a smartphone or other smart device.
  • Hospital exclusion criteria:
• Primary hospitals or private hospitals;
• Hospitals unable to cooperate with the study protocol.
  • Patient exclusion criteria:
• Patients with asthma;
• Women who are known to be pregnant or breastfeeding, or who have a positive pregnancy test before cluster randomization;
• Patients with other diseases that may affect participation in the trial, such as refractory hypertension or severe aphasia;
• Patients currently receiving psychiatric or psychological treatment that may contaminate study results;
• Expected survival time \<1 year, such as in those with malignant tumors or severe cardiopulmonary disease;
• Participation in other interventional clinical studies that may affect outcome assessment;
• Any other circumstances in which the investigator considers the patient unsuitable for participation in this study or at significant risk, such as cognitive impairment preventing understanding of and/or compliance with study procedures and/or follow-up.