NCT07660081Completed
Effects of Acetyl L-Carnitine Supplementation on Clinical, Metabolic and Inflammatory Symptoms in Obese, Diabetic, Postmenopausal Women With Osteoarthritis
Effects of Acetyl L-Carnitine Supplementation on Clinical, Metabolic and Inflammatory Symptoms in Obese, Diabetic, Postmenopausal Women With Osteoarthritis: Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 17 Sept 2026
Brief summary (registry, in English)
OA is a degenerative bone disease more common in postmenopausal women. Diabetes and obesity are common risk factors for the development of OA. The common symptoms include pain and disability of the affected joint, leading to mobility issues. Acetyl L-carnitine due to its known anti-inflammatory, chondroprotective, and improved insulin-sensitizing effects may help in alleviating the symptoms and progression of OA in obese diabetic postmenopausal women.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 100 (actual)
- First submitted
- 16 Jun 2026
- Start date
- 1 Dec 2025
- Primary completion date
- 15 Jul 2026
- Lead sponsor
- Khyber Medical University Peshawar
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT07660081
What you commit to
- Study type: Interventional
- Participants enrolled: 100
- From 1 Dec 2025 to the primary completion date, 15 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Female patients with osteoarthritis meeting the following criteria will be excluded from the study;
- Age˂55 ˃65yrs
- Post-menopausal duration of ˂2yrs
- Duration of diabetes ˂ 5years
- Patients with alcohol abuse, asthma, cardiac disease, chronic gastric problems (malabsorption, crohn's disease chronic diarrhea), non-diabetes related renal disease,ovariectomy, rheumatoid arthritis or other rheumatic inflammatory diseases, smoking
- Patients taking steroids (oral/ injections)
- Patients with a history of parathyroid and thyroid surgery/dysfunction
Who the study is looking for
- Age 55-65 years
- Duration of menopause 2-15 years.
- Duration of diabetes 5-15 years
- BMI Obese ≥30 kg/m2
- Grade≥2 K\&L on radiologic examination
Age in the registry: 55 years to 65 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Khalifa Gulnawaz Teaching Hospital, DHQ Teaching Hospital Coordinator of this site? Confirm its status | Bannu | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.