NCT07660627Recruiting
Determining Minimal Residual Disease Using ctDNA Deep Sequencing
Determination of Minimal Residual Disease by Deep ctDNA Sequencing.
Source: ClinicalTrials.gov · Last updated 24 Jun 2026
Brief summary (registry, in English)
Preoperative neoadjuvant chemotherapy is the standard treatment for locally advanced gastrointestinal tumours. However, not all patients respond to preoperative treatment. Early identification of progression during neoadjuvant chemotherapy or diagnosis of early disease relapse during adjuvant treatment is essential to modify the treatment strategy. The aim of this project is to validate ctDNA as a biomarker of molecular relapse/progression of disease.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 34 (estimated)
- First submitted
- 10 Jun 2026
- Start date
- 22 Aug 2022
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Masaryk Memorial Cancer Institute
- NCT number
- NCT07660627
What you commit to
- Study type: Interventional
- Planned participants: 34
- From 22 Aug 2022 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- not specified
Who the study is looking for
- Consent to participate in the study
- Patients with esophageal, gastric, or pancreatic cancer, stage 0-2
- Patients with locally advanced, potentially operable disease treated with systemic perioperative chemotherapy or chemoradiotherapy
- Patients with metastatic disease treated with first- to third-line palliative systemic therapy
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Masaryk Memorial Cancer Institute Coordinator of this site? Confirm its status | Brno | Czechia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.