NCT07662239Recruiting
Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention
Source: ClinicalTrials.gov · Last updated 26 Aug 2026
Brief summary (registry, in English)
This study will evaluate strategies to improve physical function and promote exercise and physical activity in adolescents and young adults (AYAs) with sarcoma. The study will assess the feasibility of a standardized triage system for referring AYAs with sarcoma to appropriate exercise and rehabilitation services, and will also examine changes in physical function and health-related quality of life before and after a 12-week personalized exercise program.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 16 Jun 2026
- Start date
- 1 Aug 2026
- Primary completion date
- 1 Aug 2027
- Lead sponsor
- Dana-Farber Cancer Institute
- Diseases
- Childhood cancers, Sarcoma
- NCT number
- NCT07662239
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 Aug 2026 to the primary completion date, 1 Aug 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently participating in physical or occupational therapy
Other illness
- Unstable cardiovascular disease in the last 6 months
- Psychiatric disorders or conditions that would preclude participation in the study intervention (e.g. untreated major depression or psychosis, untreated substance use disorder, severe personality disorder)
- Presence of medical conditions or medications that would prohibit participation in an exercise program
Other
- Pregnant
- Meeting exercise guidelines of 150 minutes of moderate intensity/75 minutes of vigorous intensity physical activity per week plus consistent strength training (at least once per week) over the past 3 months. Assessed via Godin Leisure Time Questionnaire by study staff.
- Adults unable to consent
Who the study is looking for
- Diagnosed with a bone or soft tissue sarcoma
- Age 15-39 at time of diagnosis
- Age 15 and older at time of enrollment
- Age 15-17 at time of enrollment, with assent from participant and consent from parent/legal guardian
- Established patient of the DFCI Sarcoma Center or Jimmy Fund
- Able to read and understand English (to complete required questionnaires and participate in training/coaching)
- Individuals who are not yet adults (teenagers) if they assent and their parents/legal guardians' consent to participation.
Age in the registry: 15 years to 39 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dana-Farber Cancer Institute Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Boston Children's Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.