NCT07672639Completed
Development and Validation of a Machine Learning Model for Differentiating Diabetic Kidney Disease and Non-Diabetic Kidney Disease in Type 2 Diabetes
Development and Validation of an Interpretable Machine Learning Model for Noninvasive Differentiation of Diabetic Kidney Disease and Non-Diabetic Kidney Disease in Type 2 Diabetes: A Multicenter Retrospective Cohort Study
Source: ClinicalTrials.gov · Last updated 29 Jun 2026
Brief summary (registry, in English)
This multicenter retrospective observational study aims to develop and validate an interpretable machine learning model for differentiating diabetic kidney disease (DKD) from non-diabetic kidney disease (NDKD) in patients with type 2 diabetes mellitus. Clinical, laboratory, and pathological data from biopsy-confirmed patients were collected from 14 medical centers in China. Multiple machine learning algorithms were evaluated and externally validated. The final model was implemented as a web-based clinical decision support tool.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 2201 (actual)
- First submitted
- 15 Jun 2026
- Start date
- 1 Jan 2019
- Primary completion date
- 1 Dec 2022
- Lead sponsor
- Beijing Tongren Hospital
- Diseases
- Chronic kidney disease, Type 2 diabetes
- NCT number
- NCT07672639
What you commit to
- Study type: Observational
- Participants enrolled: 2201
- From 1 Jan 2019 to the primary completion date, 1 Dec 2022
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Type 1 diabetes mellitus
- Secondary diabetes
Other
- Missing key clinical data
- Non-diagnostic kidney biopsy
- Incomplete pathological information
Who the study is looking for
- Age 18-70 years
- Diagnosis of type 2 diabetes mellitus according to ADA criteria
- Underwent kidney biopsy
- Definitive pathological diagnosis available
- Availability of required clinical and laboratory data
Age in the registry: 18 years to 70 years · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Beijing Tongren Hospital Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.