NCT07677033Recruiting
Functional Muscle-Bone Incongruity Index (FKUI): A Prospective Observational Study
Functional Muscle-Bone Incongruity Index (FKUI): Combined Evaluation of Handgrip Strength, Total Hip Bone Mineral Density, and Lumbar-Hip Bone Mineral Density Discordance in Adults Undergoing DXA
Source: ClinicalTrials.gov · Last updated 30 Jun 2026
Brief summary (registry, in English)
The Functional Muscle-Bone Incongruity Index (FKUI) is a novel approach developed to evaluate the relationship between muscle function and bone health. This prospective observational study aims to investigate the clinical applicability of FKUI, which combines handgrip strength, total hip bone mineral density (BMD), and lumbar-hip BMD discordance. Approximately 200 adult participants undergoing routine DXA assessment will be enrolled. The study will examine whether the combined evaluation of muscle function and bone health parameters provides a more comprehensive assessment of musculoskeletal status than individual measures alone.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 24 Jun 2026
- Start date
- 1 May 2026
- Primary completion date
- 1 May 2027
- Lead sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
- Diseases
- Osteoporosis
- NCT number
- NCT07677033
What you commit to
- Study type: Observational
- Planned participants: 200
- From 1 May 2026 to the primary completion date, 1 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Major trauma or fracture within the previous 6 months
Other illness
- Secondary causes of osteoporosis (e.g., hyperparathyroidism, Cushing syndrome, malignancy, or other conditions affecting bone metabolism)
- History of metabolic bone disease
- Upper extremity disorders that may significantly affect handgrip strength measurement (e.g., severe osteoarthritis, neurological disorders, major deformities)
Age
- Age younger than 18 years
Other
- DXA measurements that are technically inadequate or unsuitable for analysis
- Refusal or inability to provide written informed consent
Who the study is looking for
- Age 18 years or older
- Attendance at the Physical Medicine and Rehabilitation outpatient clinic
- Scheduled to undergo routine bone mineral density assessment by DXA as part of clinical evaluation
- Ability to perform handgrip strength testing
- Availability of lumbar spine and total hip bone mineral density measurements suitable for analysis
- Ability and willingness to provide written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey Coordinator of this site? Confirm its status | Küçükçekmece | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.