NCT07679776Enrolling by invitation
Study on Early Visual Dysfunction in Patients With Systemic Lupus Erythematosus
Source: ClinicalTrials.gov · Last updated 1 Jul 2026
Brief summary (registry, in English)
* OCT, OCTA, fundus photography, and fundus autofluorescence ( FAF ) were used to observe the fundus physiological indexes of normal subjects and SLE patients, to explore the differences of subclinical retinal damage in SLE patients with different degrees of disease activity, to summarize the changes of subclinical retina in SLE patients without organic retinopathy, and to evaluate its correlation with disease activity, which is of great significance for improving the prognosis of visual function and improving the quality of life in SLE patients. * By evaluating the visual psychophysical indicators, mainly the visual function test results of different colors and different frequencies, reflecting the functional status of the retina and the degree and characteristics of functional impairment in SLE patients with different degrees of disease activity, in order to screen out the clinical markers of SLE fundus lesions, and provide a reliable reference for the prevention and early intervention of visual impairment.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 24 Apr 2026
- Start date
- 1 Jan 2025
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- The First Affiliated Hospital of Anhui Medical University
- Diseases
- Lupus (SLE)
- NCT number
- NCT07679776
What you commit to
- Study type: Observational
- Planned participants: 100
- From 1 Jan 2025 to the primary completion date, 31 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- history of glaucoma, cataract, retinal vascular disease, retinitis pigmentosa and other eye diseases ;
- history of refractive surgery such as corneal refractive surgery and cataract surgery ;
- other major disease history or systemic lesions affecting the eye ;
- history of disease affecting cognitive function, can understand and cooperate with the examination.
Other
- obvious abnormality in cranial MRI ;
Who the study is looking for
- the best corrected visual acuity ( BCVA ) of all cases must be ≥ 1.0 according to the international standard visual acuity char;
- intraocular pressure ( IOP ) in the normal range, namely 10 mmHg ≤ IOP ≤ 21 mmHg ;
- visual field meter examination center and peripheral visual field without defect ;
- no degeneration of fundus retina ;
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Anhui Medical University Coordinator of this site? Confirm its status | Hefei | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.