NCT07680946RecruitingPhase 2
Study to Evaluate the Safety and Efficacy of Ublituximab in Participants With Schizophrenia
Evaluating Safety and Efficacy of Ublituximab in Participants With Schizophrenia
Source: ClinicalTrials.gov · Last updated 30 Oct 2026
Brief summary (registry, in English)
The main objective of this Phase 2 study is to assess the efficacy of ublituximab as measured by Positive and Negative Syndrome Scale (PANSS) total score in participants with schizophrenia.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 26 Jun 2026
- Start date
- 27 Jul 2026
- Primary completion date
- 12 Dec 2028
- Lead sponsor
- TG Therapeutics, Inc.
- Diseases
- Schizophrenia
- NCT number
- NCT07680946
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 60
- From 27 Jul 2026 to the primary completion date, 12 Dec 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any primary Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) disorder other than schizophrenia.
- Any severe or uncontrolled medical condition that could affect the participant's ability to participate.
- Note: Other protocol-specified Inclusion/Exclusion criteria may apply
Other
- Ongoing clozapine treatment.
- Risk for suicidal behavior.
Who the study is looking for
- Primary diagnosis of schizophrenia.
- Treatment-resistant.
- Requires antipsychotic treatment and is currently receiving "standard of care".
- PANSS total score between 80 and 120, inclusive at screening and baseline.
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| - Coordinator of this site? Confirm its status | Little Rock | United States | Recruiting |
| - Coordinator of this site? Confirm its status | Richardson | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.