NCT07681102Enrolling by invitation
Amplitude Modulation Frequency Comparison in Kilohertz Transcranial Magnetic Perturbation (kTMP) for Chronic Stroke
Source: ClinicalTrials.gov · Last updated 6 Jul 2026
Brief summary (registry, in English)
Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities. The goal of this proposal is to provide a first assessment of the feasibility and efficacy of an innovative non-invasive brain stimulation system, kTMP, in the treatment of motor impairment following stroke.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 7 (estimated)
- First submitted
- 26 Jun 2026
- Start date
- 10 Feb 2026
- Primary completion date
- 26 Jun 2027
- Lead sponsor
- Magnetic Tides
- Diseases
- Stroke
- NCT number
- NCT07681102
What you commit to
- Study type: Interventional
- Planned participants: 7
- From 10 Feb 2026 to the primary completion date, 26 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Botulinum toxin injections of the affected upper extremity within 3 months prior to onset of study assessments/testing through the last visit.
- Absolute contraindications related to non-invasive brain stimulation, including:
- History of seizures in the last 12 months while taking anti-epilepsy medication Presence of any metal implants in the head (excluding the mouth), such as cortical stimulators and DBS, clips, coils, shunts, stents or skull plates, cochlear implants Permanent eye liner or head tattoos Implanted electronics such as pacemakers, defibrillators, intrathecal baclofen pumps or vagus nerve stimulator History of experiencing a serious adverse event during a previous transcranial magnetic stimulation (TMS) session
Other illness
- Participants with moderate or severe cognitive impairment (MoCA \< 18).
- Language impairment or behavioral disorder that interferes with their ability to adhere to the protocol or to provide informed consent.
- Individuals who have a serious uncontrolled medical condition, including but not limited to severe cardiovascular and cardiopulmonary disease.
Other
- Participants with sensory deficits FMA-S ≥ 6/12 (with proprioception ≥ 2/4).
- Pregnancy or plans to become pregnant during the study period.
- Severe spasticity of the affected upper limb (Modified Ashworth ≥ 3).
Who the study is looking for
- Adults aged 18-80 years who have a history of a unilateral stroke ≥ 12 m prior to enrollment.
- Fugl-Meyer Assessment: Upper Extremity (FMA UE) score 20-55.
- Ability to communicate, understand, and give appropriate consent. Participants can follow two-step commands.
- Motor evoked potentials in a hand muscle when stimulating ipsilesional cortex with suprathreshold single-pulse TMS (MEP positive).
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Magnetic Tides Inc. Coordinator of this site? Confirm its status | Berkeley | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.