Label-free Femtosecond Laser Imaging Combined With the Fast Lung Artificial Intelligence Model for Rapid Intraoperative Diagnosis of Lung Surgical Specimens: A Multicentre, Prospective, Parallel-workflow, Non-inferiority Study.

Other illness

• Other conditions that, in the opinion of the investigator, make the participant unsuitable for this study.

Other

• The intraoperative specimen is insufficient and cannot simultaneously meet the requirements for routine clinical pathological diagnosis and research-related testing.
• The specimen shows severe carbonization, necrosis, compression, contamination, or improper preservation, and the investigator determines that effective imaging cannot be completed.
• The femtosecond laser imaging specimen cannot be matched with the corresponding lesion assessed by final paraffin pathology.
• Final paraffin-embedded pathological diagnosis cannot be obtained.
• The participant withdraws informed consent.

• Preoperative imaging suggests a pulmonary nodule, pulmonary space-occupying lesion, or suspected pulmonary tumor lesion.
• The participant is scheduled to undergo pulmonary wedge resection, segmentectomy, lobectomy, or other pulmonary surgery.
• Fresh lung tissue specimens can be obtained intraoperatively for femtosecond laser imaging.
• Intraoperative frozen section diagnosis is planned to assess the nature of the tumor lesion.
• Corresponding postoperative paraffin-embedded pathological diagnosis can be obtained.
• The participant or the participant's legally authorized representative has signed the written informed consent form.
• Patients had not received any antitumor treatment prior to enrollment or specimen collection, including chemotherapy, radiotherapy, targeted therapy, immunotherapy, or other systemic anticancer treatments.