NCT07683260Completed
Immune-Inflammatory Markers in Aortic Dissection
Prognostic Value of Systemic Immune-Inflammatory and Nutritional Indices for Mortality and Morbidity in Acute Aortic Dissection: A Single-Center Retrospective Study
Source: ClinicalTrials.gov · Last updated 6 Jul 2026
Brief summary (registry, in English)
Identifying early on which patients with acute aortic dissection require closer monitoring may help with care planning. If simple, inexpensive values obtained from routine blood tests can provide additional information for assessing risk, this knowledge could in the future help physicians follow their patients more effectively. The aim of this study is to investigate this possibility scientifically. It is based on the evaluation of information obtained from blood tests that are already being performed. Its purpose is to generate general knowledge that may contribute to the care of future patients. The study itself does not change decisions about your treatment; all decisions regarding your treatment and follow-up rest with your doctor, who evaluates your condition in its entirety. It is designed to evaluate the relationship between preoperative/postoperative systemic immune-inflammatory and nutritional markers (SII, NLR, PLR, CAR, PNI) and indicators of mortality and morbidity (length of stay and changes in kidney function) in patients with acute aortic dissection. The goal is to investigate the potential of easily accessible laboratory parameters to contribute to risk stratification. The relationship between the markers and outcomes will be analyzed using appropriate statistical methods. This study is based on the evaluation of information in patients' existing medical records and blood tests. The data are processed in accordance with the relevant ethical rules and privacy principles, with patient identity kept confidential. Taking part in the study does not require any additional procedure, additional blood draw, or change in treatment.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 127 (actual)
- First submitted
- 23 Jun 2026
- Start date
- 18 Jun 2026
- Primary completion date
- 20 Jun 2026
- Lead sponsor
- Bursa City Hospital
- NCT number
- NCT07683260
What you commit to
- Study type: Observational
- Participants enrolled: 127
- From 18 Jun 2026 to the primary completion date, 20 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Diagnosed with acute aortic dissection (ICD-10 code I71.0) in the emergency department but did not undergo surgery
- Chronic steroid use, immunosuppressive therapy, or recent chemotherapy
Other illness
- Hematologic disease (e.g., leukemia, lymphoma, idiopathic thrombocytopenic purpura)
- Chronic inflammatory or autoimmune disease (e.g., rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis)
- End-stage renal disease requiring hemodialysis
Lab values
- Liver failure (affects platelet production and coagulation factors)
- Missing result in any of the neutrophil, lymphocyte, or platelet blood tests
Who the study is looking for
- Diagnosis of acute aortic dissection (ICD-10 code I71.0) in the emergency department
- Underwent surgical repair for acute aortic dissection under the specified surgical codes
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bursa City Hospital Coordinator of this site? Confirm its status | Bursa | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.