NCT07696533Recruiting
ULTIMATE Study (Carotid Ultrasound Vs CT Coronary Calcium Scoring to Reclassify Symptomatic Patients With Chronic Coronary Syndrome)
Carotid Ultrasound Vs Computed Tomography (CT) Coronary Calcium Scoring to Reclassify Symptomatic Patients With Suspected Chronic Coronary Syndrome Using Risk Factor Clinical Likelihood for Obstructive Coronary Artery Disease
Source: ClinicalTrials.gov · Last updated 15 Jul 2026
Brief summary (registry, in English)
* Chest pain is one of the most common symptoms of heart disease. This could be due to narrowing in heart's blood vessels, which needs to be investigated. * Currently, people with a low risk of narrowing of heart vessels usually have a CT scan of the heart first. This scan is good at identifying those who do not have significant narrowing. However, the scan has some drawbacks, such as exposure to a small amount of radiation. * We are exploring if ultrasound of the neck vessels might give us similar kind of information as the CT scan. * You will be asked to attend the hospital for one visit to have an ultrasound scan of your neck. * The findings of your neck vessels will be compared with the CT scan of your heart vessels to see if there is a similarity.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 225 (estimated)
- First submitted
- 6 Jul 2026
- Start date
- 3 Jul 2026
- Primary completion date
- 30 Nov 2027
- Lead sponsor
- London North West Healthcare NHS Trust
- Diseases
- Coronary artery disease
- NCT number
- NCT07696533
What you commit to
- Study type: Interventional
- Planned participants: 225
- From 3 Jul 2026 to the primary completion date, 30 Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Known CAD with prior MI, PCI, CABG or any angiographic evidence of CAD (≥50% lesion in a major epicardial vessel)
- History of previous stroke or known peripheral vascular disease
Other illness
- Known significant cardiac congenital abnormalities
Age
- Age \<18 years old
- Life expectancy \< 1 years
Other
- Diagnosed ACS requiring hospitalization or urgent or emergent testing
- Pregnancy
- Unable to provide written informed consent
Who the study is looking for
- Age \> 18 years old
- Symptomatic patients with suspected CCS, judged by the clinician to require CTCA with CAC scoring, for the diagnosis of CAD
- Have a RF-CL 5-15%, as calculated using ESC guidelines
- Able to give informed consent to participate in the study and its follow up
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northwick Park Hospital Coordinator of this site? Confirm its status | Harrow | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.