NCT07697417Active, not recruiting
Multimodal Prediction of Postoperative Prognosis After Partial Nephrectomy for Endophytic Renal Cell Carcinoma
Development and External Validation of an Imaging-Clinical Multimodal Fusion Model for Predicting Postoperative Prognosis After Partial Nephrectomy in Patients With Endophytic Renal Cell Carcinoma
Source: ClinicalTrials.gov · Last updated 13 Jul 2026
Brief summary (registry, in English)
This retrospective observational cohort study aims to develop and externally validate an imaging-clinical multimodal fusion model for predicting postoperative prognosis in patients with endophytic renal cell carcinoma undergoing partial nephrectomy. Preoperative computed tomography imaging features, three-dimensional reconstruction-derived tumor characteristics, radiomics features, and clinical variables will be integrated using machine learning and deep learning approaches. The primary objective is to evaluate whether the multimodal model improves prediction of postoperative prognostic outcomes compared with single-modality models based on clinical or imaging features alone.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 406 (actual)
- First submitted
- 4 Jul 2026
- Start date
- 1 Jan 2026
- Primary completion date
- 30 May 2026
- Lead sponsor
- Tianjin Medical University Second Hospital
- Diseases
- Kidney cancer
- NCT number
- NCT07697417
What you commit to
- Study type: Observational
- Participants enrolled: 406
- From 1 Jan 2026 to the primary completion date, 30 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who underwent radical nephrectomy as the primary surgical treatment. Patients with missing or poor-quality preoperative imaging data. Patients with incomplete key clinical, pathological, or follow-up information. Patients with hereditary renal cancer syndromes. Patients with bilateral renal tumors or solitary kidney. Patients who received neoadjuvant systemic therapy before partial nephrectomy.
Who the study is looking for
- Patients diagnosed with renal cell carcinoma. Patients with endophytic renal tumors based on preoperative imaging assessment. Patients who underwent partial nephrectomy. Available preoperative contrast-enhanced computed tomography images. Available clinical, pathological, perioperative, and postoperative follow-up data.
- Age 18 years or older at the time of surgery.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tianjin Medical University Second Hospital Coordinator of this site? Confirm its status | Tianjin | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.