NCT07697664Recruiting
Moving Yourself in Space and Time: MYSTIC
Moving Yourself in Space and Time Identifying Spatial and Temporal Components of Complex Rhythmic Movement Training for People With Parkinson's Disease and Cognitive Impairment
Source: ClinicalTrials.gov · Last updated 13 Jul 2026
Brief summary (registry, in English)
This study is being done to answer the question: Do people with Parkinson's benefit from a new stepping therapy, and how do people with Parkinson's best learn new steps and rhythms set to music? Researchers will also compare individuals with Parkinson's Disease with people with Mild Cognitive Impairment, and with people with neither of these conditions. The purpose of this study is to identify principles of human-music interactions to establish underlying guiding theories for application to music-based rehabilitation for older populations with neurodegenerative disease, leading to more refined and targeted music-based rhythmic movement therapies.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 210 (estimated)
- First submitted
- 7 Jul 2026
- Start date
- 25 Mar 2022
- Primary completion date
- Dec 2028
- Lead sponsor
- Emory University
- Diseases
- Alzheimer disease, Parkinson disease
- NCT number
- NCT07697664
What you commit to
- Study type: Interventional
- Planned participants: 210
- From 25 Mar 2022 to the primary completion date, Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- On medications that could adversely affect cognition, e.g., antipsychotics, opioids, stimulants, chemotherapy, and neurologic prescriptions to treat Multiple Sclerosis. When applicable, enrollment will be delayed until dosages are stable on e.g., Aricept, Namenda, anticholinesterase inhibitors, for at least 3 months
Other illness
- Acute medical illness requiring hospitalization;
- Uncontrolled congestive heart failure;
- History of stroke in the past three years;
- Medical or physical conditions that would preclude participation (e.g., severe arthritis or mobility problems, uncontrolled hypertension or diabetes, renal failure, history of angina with activity);
- Psychotic disorders
- Confounding neurologic conditions \[e.g., active central nervous system (CNS) opportunistic infections, seizure disorders, head injury with loss of consciousness \>30 minutes, intracranial neoplasms, stroke with neurological or neuropsychiatric sequelae\]
- Substance Use Disorder, Major Depressive Disorder, and Generalized Anxiety Disorder within six months of evaluation.
Other
- Inability to perform study procedures;
- Inability to provide informed consent
Who the study is looking for
- 18 to 35 Years old
- Montreal Cognitive Assessment (MoCA) score of 26 to 30
- 50 to 79 with or without MCI
- 50 to 79 years old with Parkinson's disease (PD), who do NOT have impaired decision-making capacity
- Participants who achieve less than 150 minutes moderate or 75 minutes vigorous aerobic activity per week (as per the US Department of Health and Human Services (HHS)),
Age in the registry: 18 years to 79 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Emory University, Executive Park, Wesley Woods Coordinator of this site? Confirm its status | Atlanta | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.