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NCT07699614Recruiting

Lung Health and the Microbiome Among Adults in Botswana: the Go-hema Cohort

Determinants of Lung Health Among Batswana Adults With and Without HIV: the Go-Hema Study

Source: ClinicalTrials.gov · Last updated 13 Jul 2026

Brief summary (registry, in English)

Chronic respiratory diseases like chronic obstructive pulmonary disease (COPD) are responsible for millions of deaths each year, the majority of which occur in low- and middle-income countries (LMICs). LMICs also have high rates of abnormal lung function, including restrictive spirometric pattern (RSP), which can precede the development of chronic respiratory diseases and is associated with all-cause mortality. Additionally, LMICs in sub-Saharan Africa are home to the majority of the world's population of people with HIV (PWH). HIV increases the risk of COPD and COPD associated mortality, but the mechanisms underlying this risk are incompletely understood.

Status (registry)
Recruiting
Study type
Observational
Enrollment
900 (estimated)
First submitted
9 Jun 2025
Start date
1 Dec 2024
Primary completion date
20 Dec 2029
Lead sponsor
Duke University
Diseases
HIV
NCT number
NCT07699614

What you commit to

  • Study type: Observational
  • Planned participants: 900
  • From 1 Dec 2024 to the primary completion date, 20 Dec 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Respiratory infection in the prior 4 weeks
  • Thoracic surgery or myocardial infarction in the prior 6 weeks

Other illness

  • Active pulmonary tuberculosis

Other

  • Inability to perform spirometry including eye, abdominal, or
  • Pregnancy

Who the study is looking for

  • Adults 35 years of age or older
  • In case at a clinic in Botswana
  • Documented HIV status
  • Ability to provide informed consent

Age in the registry: 35 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Local Health Facilities in Gaborone
Coordinator of this site? Confirm its status
GaboroneBotswanaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.