NCT07699614Recruiting
Lung Health and the Microbiome Among Adults in Botswana: the Go-hema Cohort
Determinants of Lung Health Among Batswana Adults With and Without HIV: the Go-Hema Study
Source: ClinicalTrials.gov · Last updated 13 Jul 2026
Brief summary (registry, in English)
Chronic respiratory diseases like chronic obstructive pulmonary disease (COPD) are responsible for millions of deaths each year, the majority of which occur in low- and middle-income countries (LMICs). LMICs also have high rates of abnormal lung function, including restrictive spirometric pattern (RSP), which can precede the development of chronic respiratory diseases and is associated with all-cause mortality. Additionally, LMICs in sub-Saharan Africa are home to the majority of the world's population of people with HIV (PWH). HIV increases the risk of COPD and COPD associated mortality, but the mechanisms underlying this risk are incompletely understood.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 900 (estimated)
- First submitted
- 9 Jun 2025
- Start date
- 1 Dec 2024
- Primary completion date
- 20 Dec 2029
- Lead sponsor
- Duke University
- Diseases
- HIV
- NCT number
- NCT07699614
What you commit to
- Study type: Observational
- Planned participants: 900
- From 1 Dec 2024 to the primary completion date, 20 Dec 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Respiratory infection in the prior 4 weeks
- Thoracic surgery or myocardial infarction in the prior 6 weeks
Other illness
- Active pulmonary tuberculosis
Other
- Inability to perform spirometry including eye, abdominal, or
- Pregnancy
Who the study is looking for
- Adults 35 years of age or older
- In case at a clinic in Botswana
- Documented HIV status
- Ability to provide informed consent
Age in the registry: 35 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Local Health Facilities in Gaborone Coordinator of this site? Confirm its status | Gaborone | Botswana | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.