NCT07699679Not yet recruiting
Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.
Impact of Photobiomodulation in Coronary Artery Bypass Surgery: Comparison Between No-Touch and Conventional Saphenous Vein Harvesting Techniques on Clinical Outcomes, Functional Capacity, and Wound Healing: A Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG). The study will compare two techniques for saphenous vein graft harvesting: the conventional technique and the no-touch technique. Participants will be randomly allocated into four groups: conventional harvesting with sham laser, conventional harvesting with photobiomodulation, no-touch harvesting with sham laser, and no-touch harvesting with photobiomodulation. The primary objective is to evaluate the effects of photobiomodulation on wound healing and postoperative complications related to the saphenous vein harvesting site. Secondary outcomes include clinical outcomes and functional capacity after surgery. The results may contribute to improving postoperative recovery and optimizing surgical strategies in patients undergoing myocardial revascularization.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 292 (estimated)
- First submitted
- 20 Mar 2026
- Start date
- 1 Jan 2027
- Primary completion date
- 31 Aug 2027
- Lead sponsor
- Federal University of São Paulo
- Diseases
- Coronary artery disease
- NCT number
- NCT07699679
What you commit to
- Study type: Interventional
- Planned participants: 292
- From 1 Jan 2027 to the primary completion date, 31 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Emergency coronary artery bypass surgery
- Previous surgery in the lower limb that prevents saphenous vein harvesting
- Individuals with highly pigmented skin or sensibility that may alter light absorption and penetration of the photobiomodulation therapy.
Other illness
- Active infection at the surgical site or lower limb
- Severe peripheral arterial disease in the lower limbs
Other
- Hemodynamic instability preventing study protocol procedures
- Participation in another interventional clinical trial that may interfere with the outcomes of this study
- Patients unable to perform postoperative functional capacity assessments
Who the study is looking for
- Patients diagnosed with coronary artery disease scheduled to undergo elective coronary artery bypass grafting (CABG)
- Use of the saphenous vein as a graft for myocardial revascularization
- Ability to understand the study procedures and provide written informed consent
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital São Paulo, Federal University of São Paulo Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.