NCT07703358Not yet recruiting
Effect of Chromium Weight Reduction on Adult Asthma Control
Source: ClinicalTrials.gov · Last updated 14 Jul 2026
Brief summary (registry, in English)
This phase IV randomized controlled trial is designed to evaluate the effects of chromium picolinate supplementation in obese adults with stable asthma. A total of 60 participants will be recruited from Ain Shams University Hospitals and randomly assigned to receive either 400 mcg of chromium picolinate daily or a matching placebo for 12 weeks, in addition to standard asthma therapy. The study aims to explore the interaction between metabolic dysfunction and asthma, as obesity-related asthma is often associated with systemic inflammation, insulin resistance, and dyslipidemia. These factors may contribute to poorer asthma control and impaired pulmonary function, and therefore represent potential targets for adjunctive therapeutic interventions such as chromium supplementation.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 8 Apr 2026
- Start date
- 20 Aug 2026
- Primary completion date
- 20 Aug 2027
- Lead sponsor
- Cairo University
- Diseases
- Asthma
- NCT number
- NCT07703358
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 20 Aug 2026 to the primary completion date, 20 Aug 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any change in asthma medications within 4 weeks
- Use of lipid-lowering drugs or supplements in the past 3 months
- Use of Vitamin C, prostaglandin inhibitors, such as aspirin, oxalate, and antacids
Other illness
- renal or hepatic disease
- Known allergy to chromium or adverse reaction to supplementation
- History of heavy metal toxicity or chromium sensitivity
Other
- \- Recent asthma exacerbation (within the last 4 weeks)
- Current pregnancy or lactation
- Participation in another interventional study in the past month
- Being on any weight control diet
- Being on a supplement containing chromium
Who the study is looking for
- Age: 18-65 years
- Confirmed asthma diagnosis according to GINA criteria (7)
- Asthma stable for at least 4 weeks (no acute exacerbation)
- BMI of 30 kg/m² (obese category)
- Stable inhaled corticosteroid + LABA regimen in the last 4 weeks
- The patient is compliant on his asthma medication
- Willing and able to provide informed consent
- willing to continue in the study, follow investigator instructions
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.